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Traditional Asian Medicine Treatment for Childhood Cancer - Review of Controlled Clinical Studies

소아암의 한의약치료 임상 동향 - 대조군 임상연구를 중심으로

  • Kim, Younhwan (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Kim, Hanseul (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Oh, Jeongmyeong (Department of Korean Medicine, School of Korean Medicine, Pusan National University) ;
  • Lee, Hyeyoon (Department of Medicine, Graduate School, Pusan National University) ;
  • Min, Yuri (365 Korean Medicine Clinic) ;
  • Yun, Youngju (Department of Integrative Medicine, School of Korean Medicine, Pusan National University)
  • 김윤환 (부산대학교 한의학전문대학원 한의학과) ;
  • 김한슬 (부산대학교 한의학전문대학원 한의학과) ;
  • 오정명 (부산대학교 한의학전문대학원 한의학과) ;
  • 이혜윤 (부산대학교 대학원 의학과) ;
  • 민유리 (365한의원) ;
  • 윤영주 (부산대학교 한의학전문대학원 동서협진의학)
  • Received : 2020.07.24
  • Accepted : 2020.08.21
  • Published : 2020.08.31

Abstract

Objectives : To find treatment techniques and design clinical studies, this study reviewed controlled clinical studies on traditional Asian medicine treatment for childhood cancer. Methods : Literature searches were performed on four databases, such as NDSL, OASIS, PubMed, and CNKI. Studies were categorized and analyzed according to the treatment goal and we also assessed the quality of the randomized controlled trials (RCT) using Van Tulder Scale. Results : Twenty-seven studies met our inclusion criteria: 21 RCTs, 4 controlled trials, 2 Cohort studies, however only 6 among the 21 RCTs got the scores of high quality. Various interventions were used, such as herbal medicine, acupuncture, acupressure, and chuna. 7 studies were focused on cure of leukemia or solid cancer. 11 studies were performed to alleviate chemotherapy induced nausea and vomiting. 9 studies were focused on other complications of chemotherapy. Conclusions : Most of the studies reported significant effectiveness of traditional medicine treatment compared to controlled group. However we could not made a definite conclusion because of the low quality and heterogeneity of the studies included. More studies should be performed to introduce traditional Asian medicine to childhood cancer treatment.

Keywords

Acknowledgement

본 연구는 보건복지부의 재원으로 한국보건산업진흥원의 보건의료기술연구개발사업 지원에 의하여 이루어진 것임(HI18C0998).

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