한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제37권4호
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  • Pages.208-212
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  • 2020
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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Renal Lymphoma with Mesenteric Lymphomatosis in a Cat

  • Jeon, Jin-ha (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Song, Doo-won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Ro, Woong-bin (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Kim, Heyong-seok (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Lee, Ga-won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Cho, Jun-ho (Goodpapa Animal Hospital) ;
  • Jeong, Woo-chang (Africa Animal Medical Center) ;
  • Kim, Soo-hyeon (Department of Veterinary Pathology, College of Veterinary Medicine, Konkuk University) ;
  • Sur, Jung-hyang (Department of Veterinary Pathology, College of Veterinary Medicine, Konkuk University) ;
  • Park, Hee-myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 투고 : 2020.05.07
  • 심사 : 2020.07.06
  • 발행 : 2020.08.31
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초록

A 6-year-old castrated male Russian Blue cat was presented for evaluation of dyschezia. Abdominal ultrasound revealed hyperechoic nodules in both kidneys, heterogeneous mass in abdomen, and extensive mesenteric thickening with multiple hypoechoic nodules. Computed tomography showed multiple hypodense lesions in both kidneys and diffuse nodular infiltration around the mesentery. Fine needle aspirates (FNA) acquired under ultrasound guidance from the mesentery consisted of large lymphocytes which have round to irregular nuclei with granular chromatin, prominent nucleoli and a small amount of basophilic cytoplasm. Polymerase chain reaction (PCR) for antigen receptor gene rearrangement result of FNA sample revealed a T-cell malignancy. The cat died from acute renal failure after 1 cycle of modified Madison-Wisconsin L-CHOP protocol. Postmortem examination revealed bilaterally enlarged lumpy-bumpy shaped kidneys. Histopathologic examination showed an infiltration of malignant lymphocytes into the renal parenchyma and mesentery. Immunohistochemical staining of the renal sample displayed a negative expression of CD3, PAX5, MUM-1, and CD79. The clinical features and prognosis of the cat with renal lymphoma with mesenteric lymphomatosis have been described in this report.

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