Acknowledgement
I would like to offer my special thanks to the staff of Canon Medical Systems Korea for assistance with valuable comments about technology and also Vital Images Inc. for their supportive collaboration.
References
- Dharampal AS, Papadopoulou SL, Rossi A, Meijboom WB, Weustink A, Dijkshoorn M, et al. Diagnostic performance of computed tomography coronary angiography to detect and exclude left main and/or three-vessel coronary artery disease. Eur Radiol 2013;23:2934-2943 https://doi.org/10.1007/s00330-013-2935-6
- Maurer MH, Zimmermann E, Schlattmann P, Germershausen C, Hamm B, Dewey M. Indications, imaging technique, and reading of cardiac computed tomography: survey of clinical practice. Eur Radiol 2012;22:59-72 https://doi.org/10.1007/s00330-011-2239-7
- Wong DT, Ko BS, Cameron JD, Nerlekar N, Leung MC, Malaiapan Y, et al. Transluminal attenuation gradient in coronary computed tomography angiography is a novel noninvasive approach to the identification of functionally significant coronary artery stenosis: a comparison with fractional flow reserve. J Am Coll Cardiol 2013;61:1271-1279 https://doi.org/10.1016/j.jacc.2012.12.029
- Choi JH, Min JK, Labounty TM, Lin FY, Mendoza DD, Shin DH, et al. Intracoronary transluminal attenuation gradient in coronary CT angiography for determining coronary artery stenosis. JACC Cardiovasc Imaging 2011;4:1149-1157 https://doi.org/10.1016/j.jcmg.2011.09.006
- Ko BS, Wong DT, Norgaard BL, Leong DP, Cameron JD, Gaur S, et al. Diagnostic performance of transluminal attenuation gradient and noninvasive fractional flow reserve derived from 320-detector row CT angiography to diagnose hemodynamically significant coronary stenosis: an NXT substudy. Radiology 2016;279:75-83 https://doi.org/10.1148/radiol.2015150383
- Stuijfzand WJ, Danad I, Raijmakers PG, Marcu CB, Heymans MW, van Kuijk CC, et al. Additional value of transluminal attenuation gradient in CT angiography to predict hemodynamic significance of coronary artery stenosis. JACC Cardiovasc Imaging 2014;7:374-386 https://doi.org/10.1016/j.jcmg.2013.12.013
- Takx RA, Sucha D, Park J, Leiner T, Hoffmann U. Sublingual nitroglycerin administration in coronary computed tomography angiography: a systematic review. Eur Radiol 2015;25:3536-3542 https://doi.org/10.1007/s00330-015-3791-3
- Feldman RL, Pepine CJ, Curry RC Jr, Conti CR. Coronary arterial responses to graded doses of nitroglycerin. Am J Cardiol 1979;43:91-97 https://doi.org/10.1016/0002-9149(79)90050-X
- Scanlon PJ, Faxon DP, Audet AM, Carabello B, Dehmer GJ, Eagle KA, et al. ACC/AHA guidelines for coronary angiography. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Coronary Angiography). Developed in collaboration with the Society for Cardiac Angiography and Interventions. J Am Coll Cardiol 1999;33:1756-1824 https://doi.org/10.1016/S0735-1097(99)00126-6
- Johnson PT, Eng J, Pannu HK, Fishman EK. 64-MDCT angiography of the coronary arteries: nationwide survey of patient preparation practice. AJR Am J Roentgenol 2008;190:743-747 https://doi.org/10.2214/AJR.07.2620
- Park EA, Lee W, Park SJ, Kim YK, Hwang HY. Influence of coronary artery diameter on intracoronary transluminal attenuation gradient during CT angiography. JACC Cardiovasc Imaging 2016;9:1074-1083 https://doi.org/10.1016/j.jcmg.2015.10.028
- Kang EJ, Kim MH, De Jin C, Seo J, Kim DW, Yoon SK, et al. Noninvasive detection of coronary vasospastic angina using a double-acquisition coronary CT angiography protocol in the presence and absence of an intravenous nitrate: a pilot study. Eur Radiol 2017;27:1136-1147 https://doi.org/10.1007/s00330-016-4476-2
- Jin C, Kim MH, Kang EJ, Cho YR, Park TH, Lee KN, et al. Assessing vessel tone during coronary artery spasm by dual-acquisition multidetector computed tomography angiography. Cardiology 2018;139:25-32 https://doi.org/10.1159/000478926
- Fujimoto S, Giannopoulos AA, Kumamaru KK, Matsumori R, Tang A, Kato E, et al. The transluminal attenuation gradient in coronary CT angiography for the detection of hemodynamically significant disease: can all arteries be treated equally? Br J Radiol 2018;91:20180043
- Weustink AC, Meijboom WB, Mollet NR, Otsuka M, Pugliese F, van Mieghem C, et al. Reliable high-speed coronary computed tomography in symptomatic patients. J Am Coll Cardiol 2007;50:786-794 https://doi.org/10.1016/j.jacc.2007.04.068
- Vanhoenacker PK, Heijenbrok-Kal MH, Van Heste R, Decramer I, Van Hoe LR, Wijns W, et al. Diagnostic performance of multidetector CT angiography for assessment of coronary artery disease: meta-analysis. Radiology 2007;244:419-428 https://doi.org/10.1148/radiol.2442061218
- Cademartiri F, Seitun S, Clemente A, La Grutta L, Toia P, Runza G, et al. Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography. Cardiovasc Diagn Ther 2017;7:129-150 https://doi.org/10.21037/cdt.2017.03.22
- Kato E, Fujimoto S, Takamura K, Kawaguchi Y, Aoshima C, Hiki M, et al. Clinical significance of transluminal attenuation gradient in 320-row area detector coronary CT angiography. Heart Vessels 2018;33:462-469 https://doi.org/10.1007/s00380-017-1081-5
- Dodge JT Jr, Brown BG, Bolson EL, Dodge HT. Lumen diameter of normal human coronary arteries. Influence of age, sex, anatomic variation, and left ventricular hypertrophy or dilation. Circulation 1992;86:232-246 https://doi.org/10.1161/01.CIR.86.1.232
- Steigner ML, Mitsouras D, Whitmore AG, Otero HJ, Wang C, Buckley O, et al. Iodinated contrast opacification gradients in normal coronary arteries imaged with prospectively ECG-gated single heart beat 320-detector row computed tomography. Circ Cardiovasc Imaging 2010;3:179-186 https://doi.org/10.1161/CIRCIMAGING.109.854307
- Okada M, Nakashima Y, Nomura T, Miura T, Nao T, Yoshimura M, et al. Coronary vasodilation by the use of sublingual nitroglycerin using 64-slice dual-source coronary computed tomography angiography. J Cardiol 2015;65:230-236 https://doi.org/10.1016/j.jjcc.2014.05.012
- Harrison DG, Bates JN. The nitrovasodilators. New ideas about old drugs. Circulation 1993;87:1461-1467 https://doi.org/10.1161/01.CIR.87.5.1461
- Abrams J. Beneficial actions of nitrates in cardiovascular disease. Am J Cardiol 1996;77:31C-37C https://doi.org/10.1016/S0002-9149(96)00186-5
- Divakaran S, Loscalzo J. The role of nitroglycerin and other nitrogen oxides in cardiovascular therapeutics. J Am Coll Cardiol 2017;70:2393-2410 https://doi.org/10.1016/j.jacc.2017.09.1064
- Feldman RL, Marx JD, Pepine CJ, Conti CR. Analysis of coronary responses to various doses of intracoronary nitroglycerin. Circulation 1982;66:321-327 https://doi.org/10.1161/01.CIR.66.2.321
- Cohen MV, Kirk ES. Differential response of large and small coronary arteries to nitroglycerin and angiotensin. Autoregulation and tachyphylaxis. Circ Res 1973;33:445-453 https://doi.org/10.1161/01.RES.33.4.445