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CT and MRI Findings of Small Bowel Involvement of Amyloidosis Mimicking Small Bowel Polyposis Syndrome: a Case Report

  • Kang, Dong Min (Department of Radiology, Wonkwang University School of Medicine & Hospital) ;
  • Lee, Young Hwan (Department of Radiology, Wonkwang University School of Medicine & Hospital) ;
  • Kim, Youe Ree (Department of Radiology, Wonkwang University School of Medicine & Hospital) ;
  • Yoon, Kwon-Ha (Department of Radiology, Wonkwang University School of Medicine & Hospital) ;
  • Yun, Ki Jung (Department of Pathology, Wonkwang University School of Medicine & Hospital)
  • Received : 2019.12.22
  • Accepted : 2020.03.26
  • Published : 2020.06.30

Abstract

Amyloidosis is an all-inclusive disease of deposition of amyloid proteins in the extracellular spaces, which in localized or systemic form cause tissue damage and dysfunction. Herein, we report a case of small bowel involvement of systemic amyloidosis presenting with multiple polypoid wall thickening mimicking small bowel polyposis syndrome in an age 75 male. Interestingly, polypoid wall thickening and amyloidoma showed hypointensity on T2-weighted images. To our knowledge, there has been no literature describing MRI findings of poylpoid wall thickening and amyloidoma. Although the underlying mechanisms are unclear and need validation, hypointensity on T2-weighted images could be valuable in diagnosing small bowel involvement of amyloidosis in patients presenting with poylpoid wall thickening and amyloidoma.

Keywords

References

  1. Benson MD, Buxbaum JN, Eisenberg DS, et al. Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee. Amyloid 2018;25:215-219 https://doi.org/10.1080/13506129.2018.1549825
  2. Kim SH, Han JK, Lee KH, et al. Abdominal amyloidosis: spectrum of radiological findings. Clin Radiol 2003;58:610-620 https://doi.org/10.1016/S0009-9260(03)00142-9
  3. Mainenti PP, Segreto S, Mancini M, et al. Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation. World J Gastroenterol 2010;16:2566-2570 https://doi.org/10.3748/wjg.v16.i20.2566
  4. Ozcan HN, Haliloglu M, Sokmensuer C, Akata D, Ozmen M, Karcaaltincaba M. Imaging for abdominal involvement in amyloidosis. Diagn Interv Radiol 2017;23:282-285 https://doi.org/10.5152/dir.2017.16484
  5. Saindane AM, Losada M, Macari M. Focal amyloidoma of the small bowel mimicking adenocarcinoma on CT. AJR Am J Roentgenol 2005;185:1187-1189 https://doi.org/10.2214/AJR.04.1134
  6. Rajkumar SV, Dispenzieri A, Kyle RA. Monoclonal gammopathy of undetermined significance, Waldenstrom macroglobulinemia, AL amyloidosis, and related plasma cell disorders: diagnosis and treatment. Mayo Clin Proc 2006;81:693-703 https://doi.org/10.4065/81.5.693
  7. Georgiades CS, Neyman EG, Barish MA, Fishman EK. Amyloidosis: review and CT manifestations. Radiographics 2004;24:405-416 https://doi.org/10.1148/rg.242035114
  8. Tada S, Iida M, Yao T, et al. Gastrointestinal amyloidosis: radiologic features by chemical types. Radiology 1994;190:37-42 https://doi.org/10.1148/radiology.190.1.8259424
  9. Gillmore JD, Hawkins PN. Pathophysiology and treatment of systemic amyloidosis. Nat Rev Nephrol 2013;9:574-586 https://doi.org/10.1038/nrneph.2013.171