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Multiple Myeloma Similar to Traumatic Trigeminal Neuropathy after Dental Treatment: Case Report

  • Lee, Ji-Yeon (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Ju, Hye-Min (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Lee, Hae-Ohk (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Jeon, Hye-Mi (Dental Clinic Center, Pusan National University Hospital) ;
  • Kim, Kyung-Hee (Department of Oral Medicine, Inje University Busan Paik Hospital) ;
  • Jeong, Sung-Hee (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Ahn, Yong-Woo (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Ok, Soo-Min (Department of Oral Medicine, Dental Research Institute, Dental and Life Science Institute, Pusan National University School of Dentistry)
  • Received : 2020.06.03
  • Accepted : 2020.06.11
  • Published : 2020.06.30

Abstract

Multiple myeloma is malignant neoplasm of plasma cells. Mandible lesions are rarely the first symptoms of multiple myeloma. While sensory dysfunction and pain are the main symptoms of traumatic trigeminal neuropathy, the same oral symptoms can appear in cases of multiple myeloma with developed mandible lesions. In addition, if the radiological osteoporosis or lytic lesion is seen in older patients, further examination is required to find the cause of the symptoms. In this paper, we present a case that was tentatively diagnosed as traumatic trigeminal neuropathy after left third molar extraction, but later confirmed as multiple myeloma.

Keywords

References

  1. Penarrocha MA, Penarrocha D, Bagan JV, Penarrocha M. Posttraumatic trigeminal neuropathy. A study of 63 cases. Med Oral Patol Oral Cir Bucal 2012;17:e297-e300. https://doi.org/10.4317/medoral.17401
  2. Benoliel R, Zadik Y, Eliav E, Sharav Y. Peripheral painful traumatic trigeminal neuropathy: clinical features in 91 cases and proposal of novel diagnostic criteria. J Orofac Pain 2012;26:49-58.
  3. Benoliel R, Teich S, Eliav E. Painful traumatic trigeminal neuropathy. Oral Maxillofac Surg Clin North Am 2016;28:371-380. https://doi.org/10.1016/j.coms.2016.03.002
  4. Benoliel R, Kahn J, Eliav E. Peripheral painful traumatic trigeminal neuropathies. Oral Dis 2012;18:317-332. https://doi.org/10.1111/j.1601-0825.2011.01883.x
  5. Mohammadi Z. Endodontics-related paresthesia of the mental and inferior alveolar nerves: an updated review. J Can Dent Assoc 2010;76:a117.
  6. Sreeja C, Vijayabanu B, Vijayalakshmi D, Devi M, Ramakrishnan K, Dhivya K. Multiple myeloma involving mandible: in an elderly female. J Pharm Bioallied Sci 2015;7(Suppl 2):S763-S765.
  7. Ali IK, Parate AR, Kasat VO, Dora A. Multiple myeloma with primary manifestation in the mandible. Cureus 2018;10:e2265.
  8. Dayisoylu EH, Ceneli O, Coskunoglu EZ. Solitary plasmacytoma of the mandible: an uncommon entity. Iran Red Crescent Med J 2016;18:e22932.
  9. Ramaiah KK, Joshi V, Thayi SR, Sathyanarayana P, Patil P, Ahmed Z. Multiple myeloma presenting with a maxillary lesion as the first sign. Imaging Sci Dent 2015;45:55-60. https://doi.org/10.5624/isd.2015.45.1.55
  10. Fregnani ER, Leite AA, Parahyba CJ, Nesrallah AC, Ramos-Perez FM, Perez DC. Mandibular destructive radiolucent lesion: the first sign of multiple myeloma. J Clin Exp Dent 2016;8:e465-e468. https://doi.org/10.4317/jced.52832
  11. Kyle RA, Gertz MA, Witzig TE, et al. Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin Proc 2003;78:21-33. https://doi.org/10.4065/78.1.21
  12. Silbert BI, Kolm S, Silbert PL. Postprocedural inflammatory inferior alveolar neuropathy: an important differential diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;115:e1-e3. https://doi.org/10.1016/j.oooo.2011.08.017
  13. Talamo G, Farooq U, Zangari M, et al. Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma. Clin Lymphoma Myeloma Leuk 2010;10:464-468. https://doi.org/10.3816/CLML.2010.n.080
  14. Fazel F, Bassa F. An approach to the diagnosis and management of multiple myeloma. S Afr Med J 2019;109:723-727. https://doi.org/10.7196/SAMJ.2019.v109i10.14376
  15. Almeida TMX, Cavalcanti EFF, Freitas ADS, Magalhaes RJP, Maiolino A, Torres SR. Can dentists detect multiple myeloma through oral manifestations? Rev Bras Hematol Hemoter 2018;40:43-49. https://doi.org/10.1055/s-0037-1606274