Medical Lasers

  • 제9권2호
  • /
  • Pages.95-102
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  • 2020
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  • 2287-8300(pISSN)
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  • 2288-0224(eISSN)
대한의학레이저학회 (Korean Society for Laser Medicine and Surgery)
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DOI QR코드

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Phototherapy in Allergic Rhinitis: From In Vitro Studies to Clinical Trials

  • Yoo, Shin Hyuk (Department of Otorhinolaryngology, Dankook University College of Medicine) ;
  • Chung, Young-Jun (Department of Otorhinolaryngology, Dankook University College of Medicine) ;
  • Bae, Jun-Sang (Department of Otorhinolaryngology, Dankook University College of Medicine) ;
  • Mo, Ji-Hun (Department of Otorhinolaryngology, Dankook University College of Medicine)
  • 투고 : 2020.11.24
  • 심사 : 2020.11.28
  • 발행 : 2020.12.31
⟨ 이전 논문 다음 논문 ⟩

초록

Phototherapy has a profound immunosuppressive effect and is widely used for the treatment of inflammatory skin diseases. Since allergic rhinitis (AR) shares several common pathologic features with atopic dermatitis, intranasal phototherapy is a novel approach for treating AR. Phototherapy reduces the antigen presenting capacity of dendritic cells, induces apoptosis of immune cells, and inhibits synthesis and release of pro-inflammatory mediators from inflammatory cells. The effectiveness of phototherapy for AR has been extensively researched: from in vitro studies to several clinical trials. Data indicates the potential of intranasal phototherapy as an alternative treatment for AR as well as other inflammatory mucosal diseases. In this review, we introduce the in vitro, in vivo studies, and clinical trials which demonstrated the effect of phototherapy on AR.

키워드

과제정보

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (2019R1F1A1060589) and funded by the Ministry of Education (2018R1D1A3B07048683). This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2020R1A6A1A03043283).

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