Medical Lasers

Korean Society for Laser Medicine and Surgery (대한의학레이저학회)
권호 표지
DOI QR코드

DOI QR Code

Koebner Phenomenon Delays Therapeutic Effect of Pulsed Dye Laser on Refractory Psoriasis

  • Park, Jae Wan (Department of Dermatology, Chung-Ang University College of Medicine) ;
  • Shin, Sun Hye (Department of Dermatology, Chung-Ang University College of Medicine) ;
  • Han, Hye Sung (Department of Dermatology, Chung-Ang University College of Medicine) ;
  • Yoo, Kwang Ho (Department of Dermatology, Chung-Ang University College of Medicine)
  • Received : 2020.04.22
  • Accepted : 2020.05.07
  • Published : 2020.06.30
⟨ Previous Next ⟩

Abstract

Psoriasis is a common chronic inflammatory skin disease that is histopathologically characterized by abnormal differentiation and hyperproliferation of keratinocytes, infiltration of T lymphocytes, and alternations of the dermal vasculature. Pulsed dye laser (PDL) is commonly used to treat cutaneous vascular lesions, and it has been studied for the treatment of localized psoriatic lesions. A 30-year-old female patient with refractory psoriasis on her forehead was treated using PDL. After two sessions, the size of the psoriatic lesion increased, which might have occurred due to koebnerization. As the patient continued to receive PDL treatment, the lesion showed significant improvement with no recurrence on the one-year follow-up. We present here a case of refractory psoriasis treated with PDL and demonstrates an association between a delayed therapeutic effect and the Koebner phenomenon.

Keywords

References

  1. Hacker SM, Rasmussen JE. The effect of flash lamp-pulsed dye laser on psoriasis. Arch Dermatol 1992;128:853-5.
  2. Erceg A, de Jong EM, van de Kerkhof PC, Seyger MM. The efficacy of pulsed dye laser treatment for inflammatory skin diseases: a systematic review. J Am Acad Dermatol 2013;69:609-15.e8. https://doi.org/10.1016/j.jaad.2013.03.029
  3. De Leeuw J, Van Lingen RG, Both H, Tank B, Nijsten T, Martino Neumann HA. A comparative study on the efficacy of treatment with 585 nm pulsed dye laser and ultraviolet B-TL01 in plaque type psoriasis. Dermatol Surg 2009;35:80-91. https://doi.org/10.1097/00042728-200901000-00012
  4. Zhang P, Wu MX. A clinical review of phototherapy for psoriasis. Lasers Med Sci 2018;33:173-80. https://doi.org/10.1007/s10103-017-2360-1
  5. Sagi L, Trau H. The Koebner phenomenon. Clin Dermatol 2011;29:231-6. https://doi.org/10.1016/j.clindermatol.2010.09.014