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Safety and Efficacy of Left Atrial Appendage Excision Using a Vascular Stapler

  • Park, Ji Hyeon (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Sohn, Suk Ho (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Choi, Jae Woong (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Park, Eun Ah (Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Hwang, Ho Young (Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine)
  • Received : 2019.11.13
  • Accepted : 2019.12.11
  • Published : 2020.06.05

Abstract

Background: This study was conducted to evaluate the safety and efficacy of left atrial appendage (LAA) excision using a vascular stapler. Methods: Fifty consecutive patients (mean age, 68±9 years) who underwent LAA excision using a vascular stapler during concomitant cardiac surgery were enrolled. In all patients, the excision site was evaluated using computed tomography at a median of 7 days (interquartile range, 5-13.3 days) postoperatively. The safety endpoint of this study was the occurrence of LAA excision-related events, which were defined as bleeding from the excision site that required reinforcement sutures or reoperation due to excision site bleeding. The efficacy endpoint was LAA excision failure, which was defined as a remnant LAA (a stump >1 cm in maximum length) or extravasation of radiocontrast dye. Results: LAAs were excised using 60- and 45-mm vascular staplers in 49 patients and 1 patient, respectively. Reinforcement sutures were needed in 4 patients due to staple-line bleeding and in 4 patients due to bleeding of the surrounding tissues. No patient underwent reoperation due to staple-related bleeding. A remnant LAA was observed in 2 patients, while extravasation of radiocontrast dye was not observed in any patients. Conclusion: LAA excision using a vascular stapler may be an effective technique for LAA exclusion. Delicate handling of the stapler device and LA tissue is required to prevent procedure-related complications.

Keywords

References

  1. Doty DB. Surgical treatment of atrial fibrillation. Heart Lung Circ 2004;13:280-7. https://doi.org/10.1016/j.hlc.2004.02.020
  2. Narayan SM, Cain ME, Smith JM. Atrial fibrillation. Lancet 1997;350:943-50. https://doi.org/10.1016/S0140-6736(97)06359-9
  3. Gillinov AM, Blackstone EH, McCarthy PM. Atrial fibrillation: current surgical options and their assessment. Ann Thorac Surg 2002;74:2210-7. https://doi.org/10.1016/S0003-4975(02)03977-2
  4. Sherif HM. The developing pulmonary veins and left atrium: implications for ablation strategy for atrial fibrillation. Eur J Cardiothorac Surg 2013;44:792-9. https://doi.org/10.1093/ejcts/ezt098
  5. Blackshear JL, Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg 1996;61:755-9. https://doi.org/10.1016/0003-4975(95)00887-X
  6. Leung DY, Black IW, Cranney GB, Hopkins AP, Walsh WF. Prognostic implications of left atrial spontaneous echo contrast in nonvalvular atrial fibrillation. J Am Coll Cardiol 1994;24:755-62. https://doi.org/10.1016/0735-1097(94)90025-6
  7. DiSesa VJ, Tam S, Cohn LH. Ligation of the left atrial appendage using an automatic surgical stapler. Ann Thorac Surg 1988;46:652-3. https://doi.org/10.1016/S0003-4975(10)64728-5
  8. Salzberg SP, Plass A, Emmert MY, et al. Left atrial appendage clip occlusion: early clinical results. J Thorac Cardiovasc Surg 2010;139:1269-74. https://doi.org/10.1016/j.jtcvs.2009.06.033
  9. Stoddard MF, Dawkins PR, Prince CR, Ammash NM. Left atrial appendage thrombus is not uncommon in patients with acute atrial fibrillation and a recent embolic event: a transesophageal echocardiographic study. J Am Coll Cardiol 1995;25:452-9. https://doi.org/10.1016/0735-1097(94)00396-8
  10. Lee R, Vassallo P, Kruse J, et al. A randomized, prospective pilot comparison of 3 atrial appendage elimination techniques: internal ligation, stapled excision, and surgical excision. J Thorac Cardiovasc Surg 2016;152:1075-80. https://doi.org/10.1016/j.jtcvs.2016.06.009
  11. Gillinov AM, Pettersson G, Cosgrove DM. Stapled excision of the left atrial appendage. J Thorac Cardiovasc Surg 2005;129:679-80. https://doi.org/10.1016/j.jtcvs.2004.07.039
  12. Salzberg SP, Gillinov AM, Anyanwu A, Castillo J, Filsoufi F, Adams DH. Surgical left atrial appendage occlusion: evaluation of a novel device with magnetic resonance imaging. Eur J Cardiothorac Surg 2008;34:766-70. https://doi.org/10.1016/j.ejcts.2008.05.058
  13. Katz ES, Tsiamtsiouris T, Applebaum RM, Schwartzbard A, Tunick PA, Kronzon I. Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiograhic study. J Am Coll Cardiol 2000;36:468-71. https://doi.org/10.1016/S0735-1097(00)00765-8
  14. Kuh JH, Song JY, Kim TY, Kim JH, Choi JB. Treatment of atrial fibrillation in elderly patients with the Cox Maze procedure concurrently with other cardiac operations. Korean J Thorac Cardiovasc Surg 2017;50:171-6. https://doi.org/10.5090/kjtcs.2017.50.3.171
  15. Healey JS, Crystal E, Lamy A, et al. Left Atrial Appendage Occlusion Study (LAAOS): results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke. Am Heart J 2005;150:288-93. https://doi.org/10.1016/j.ahj.2004.09.054
  16. Ismail TF, Panikker S, Markides V, et al. CT imaging for left atrial appendage closure: a review and pictorial essay. J Cardiovasc Comput Tomogr 2015;9:89-102. https://doi.org/10.1016/j.jcct.2015.01.011