Journal of Medicine and Life Science

Institute for Medical Science (제주대학교 의과학연구소)
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Recommendation for conducting process of an epidemiological survey in respiratory syncytial virus infection

호흡기세포융합바이러스감염증 역학조사 수행절차 제안

  • Kim, Dae Soon (Department of Public Health, Chungnam National University Graduate School) ;
  • Bae, Jong-Myon (Department of Preventive Medicine, Jeju National University College of Medicine)
  • 김대순 (충남대학교 일반대학원 보건학과) ;
  • 배종면 (제주대학교 의과대학 예방의학교실)
  • Received : 2019.11.07
  • Accepted : 2019.12.17
  • Published : 2020.04.30
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Abstract

As respiratory syncytial virus(RSV) is transmitted either via directly contact with an infected case or via indirectly contaminated fomites or skin, the major preventive measures are strict hand hygiene, early detection of transmitted sources, and rapid isolation of RSV patients. Especially early detection of hidden cases is the most critical control measure when an index case was notified in a postpartum center. The Guideline of Korea Centers for Diseases Control and Prevention defines potential contacts in an epidemiologic survey as admitted newborns, parents of index cases, center's workers, and visitors for 10 days before the first diagnosis day of index case. However, it needs to classify potential contacts in more detail in order to conduct a successful survey. Authors conducted to search related literatures and appraise the evidences. Firstly, potential contacts would be classified into RSV-related symptomatic contacts(SxC) and asymptomatic contacts. And then, mother, caring workers, and visitors of the index cases among asymptomatic contacts would be defined as the asymptomatic close contacts(ASCC). Finally, the rest would be defined as the asymptomatic regular contacts(ASRC). The defined test using reverse transcription-PCR is applied to SxC and ASCC, and decision of isolation or regular activities are made according to the results. The rapid antigen detection test kits are applied to ASRC. These suggestions might be helpful to detect hidden cases earlier and prevent a further infection.

Keywords

References

  1. Hall CB, Weinberg GA, Iwane MK, Blumkin AK, Edwards KM, Staat MA, et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med 2009;360:588-98. https://doi.org/10.1056/NEJMoa0804877
  2. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 2010;375:1545-55. https://doi.org/10.1016/S0140-6736(10)60206-1
  3. Piedimonte G, Perez MK. Respiratory syncytial virus infection and bronchiolitis. Pediatr Rev 2014;35:519-30. https://doi.org/10.1542/pir.35-12-519
  4. Hall CB, Simoes EA, Anderson LJ. Clinical and epidemiologic features of respiratory syncytial virus. Curr Top Microbiol Immunol 2013;372:39-57.
  5. Ryu S, Kim BI, Chun BC. An outbreak of respiratory tract infection due to Respiratory Syncytial Virus-B in a postpartum center. J Infect Chemother 2018;24:689-94. https://doi.org/10.1016/j.jiac.2018.06.010
  6. Kuhdari P, Brosio F, Malaventura C, Stefanati A, Orsi A, Icardi G, et al. Human respiratory syncytial virus and hospitalization in young children in Italy. Ital J Pediatr 2018;44:50. https://doi.org/10.1186/s13052-018-0492-y
  7. Mohapatra SS, Boyapalle S. Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma. Clin Microbiol Rev 2008;21:495-504. https://doi.org/10.1128/CMR.00054-07
  8. Reis J, Shaman J. Retrospective parameter estimation and forecast of respiratory syncytial virus in the United States. PLoS Comput Biol 2016;12:e1005133. https://doi.org/10.1371/journal.pcbi.1005133
  9. Falsey AR, Walsh EE. Respiratory syncytial virus infection in adults. Clin Microbiol Rev 2000;13:371-84. https://doi.org/10.1128/CMR.13.3.371-384.2000
  10. Haber N. Respiratory syncytial virus infection in elderly adults. Med Mal Infect 2018;48:377-82. https://doi.org/10.1016/j.medmal.2018.01.008
  11. Korea Centers for Disease Control and prevention. 2017 Guideline for Controlling Infections in postpartum centers. Available from: http://www.cdc.go.kr/CDC/together/CdcKrTogether0302.jsp?menuIds=HOME006-MNU2804-MNU3027-MNU2979&cid=138065
  12. Park WJ, Yoo SJ, Lee SH, Chung JW, Jang KH, Moon JD. Respiratory syncytial virus outbreak in the basic military training cAMP of the republic of Korea Air Force. J Prev Med Public Health 2015;48:10-7. https://doi.org/10.3961/jpmph.14.037
  13. Casiano-Colon AE, Hulbert BB, Mayer TK, Walsh EE, Falsey AR. Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults. J Clin Virol 2003;28:169-74. https://doi.org/10.1016/S1386-6532(03)00002-7
  14. Falsey AR, Formica MA, Walsh EE. Diagnosis of respiratory syncytial virus infection: comparison of reverse transcription-PCR to viral culture and serology in adults with respiratory illness. J Clin Microbiol 2002;40:817-20. https://doi.org/10.1128/JCM.40.3.817-820.2002
  15. Walsh EE. Respiratory syncytial virus infection in adults. Semin Respir Crit Care Med 2011;32:423-32. https://doi.org/10.1055/s-0031-1283282
  16. Miernyk K, Bulkow L, DeByle C, Chikoyak L, Hummel KB, Hennessy T, et al. Performance of a rapid antigen test (Binax $NOW^{(R)}$ RSV) for diagnosis of respiratory syncytial virus compared with real-time polymerase chain reaction in a pediatric population. J Clin Virol 2011;50:240-3. https://doi.org/10.1016/j.jcv.2010.11.011
  17. Caram LB, Chen J, Taggart EW, Hillyard DR, She R, Polage CR, et al. Respiratory syncytial virus outbreak in a long-term care facility detected using reverse transcriptase polymerase chain reaction: an argument for real-time detection methods. J Am Geriatr Soc 2009;57:482-5. https://doi.org/10.1111/j.1532-5415.2008.02153.x
  18. Falsey AR, McCann RM, Hall WJ, Criddle MM. Evaluation of four methods for the diagnosis of respiratory syncytial virus infection in older adults. J Am Geriatr Soc 1996;44:71-3. https://doi.org/10.1111/j.1532-5415.1996.tb05641.x
  19. Bissonnette L, Bergeron MG. Diagnosing infections-current and anticipated technologies for point-of-care diagnostics and homebased testing. Clin Microbiol Infect 2010;16:1044-53. https://doi.org/10.1111/j.1469-0691.2010.03282.x
  20. Chartrand C, Tremblay N, Renaud C, Papenburg J. Diagnostic accuracy of rapid antigen detection tests for respiratory syncytial virus infection: systematic review and meta-analysis. J Clin Microbiol 2015;53:3738-49. https://doi.org/10.1128/JCM.01816-15
  21. Griffiths C, Drews SJ, Marchant DJ. Respiratory syncytial virus: infection, detection, and new options for prevention and treatment. Clin Microbiol Rev 2017;30:277-319. https://doi.org/10.1128/CMR.00010-16
  22. Vecino-Ortiz AI, Goldenberg SD, Douthwaite ST, Cheng CY, Glover RE, Mak C, et al. Impact of a multiplex PCR point-of-care test for influenza A/B and respiratory syncytial virus on an acute pediatric hospital ward. Diagn Microbiol Infect Dis 2018;91:331-5. https://doi.org/10.1016/j.diagmicrobio.2018.03.013
  23. Kestler M, Munoz P, Mateos M, Adrados D, Bouza E. Respiratory syncytial virus burden among adults during flu season: an underestimated pathology. J Hosp Infect 2018;100:463-8. https://doi.org/10.1016/j.jhin.2018.03.034
  24. Tran LC, Tournus C, Dina J, Morello R, Brouard J, Vabret A. $SOFIA^{(R)}RSV$: prospective laboratory evaluation and implementation of a rapid diagnostic test in a pediatric emergency ward. BMC Infect Dis 2017;17:452. https://doi.org/10.1186/s12879-017-2557-8
  25. Kim HJ, Choi SM, Lee J, Park YS, Lee CH, Yim JJ, et al. Respiratory virus of severe pneumonia in South Korea: Prevalence and clinical implications. PLoS One 2018;13:e0198902. https://doi.org/10.1371/journal.pone.0198902
  26. Ramirez JA. RSV infection in the adult population. Manag Care 2008;17:13-5, discussion 18-9.