Journal of Yeungnam Medical Science

영남대 의대 학술지 편집위원회 (Yeungnam University College of Medicine, Yeungnam University Institute Medical Science)
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Extramedullary tanycytic ependymoma of the lumbar spinal cord

  • Kim, Dong Ja (Department of Forensic Medicine, School of Medicine, Kyungpook National University) ;
  • Han, Man-Hoon (Department of Pathology, Kyungpook National University Hospital) ;
  • Lee, SangHan (Department of Forensic Medicine, School of Medicine, Kyungpook National University)
  • 투고 : 2019.09.24
  • 심사 : 2019.11.04
  • 발행 : 2020.04.30
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초록

Tanycytic ependymoma is a rare variant of ependymoma that commonly affects the cervical and thoracic spinal cord. It usually arises as intramedullary lesions, and extramedullary cases are extremely rare. We report a case of a 44-year-old woman who was diagnosed with tanycytic ependymoma in her lumbar spine at level 2-3. The tumor mass developed in an intradural extramedullary location. Histopathologically, tanycytic ependymoma can be misdiagnosed as schwannoma or pilocytic astrocytoma. Immunohistochemical findings such as strong positivity for glial fibrillary acidic protein, perinuclear dot-like positive patterns for epithelial membrane antigen, and focal positivity for S100 protein are helpful in diagnosing tanycytic ependymoma. It is important to be aware of this rare tumor to ensure appropriate patient management and accurate prognosis.

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참고문헌

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피인용 문헌

  1. Intradural extramedullary tanycytic ependymoma of the cervical spine: A case report vol.26, 2020, https://doi.org/10.1016/j.inat.2021.101319