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Co-occurrence of apocrine adenocarcinoma and invasive mammary-type ductal carcinoma in extramammary Paget disease of the axilla

  • Jang, Seung Bin (Department of Plastic and Reconstructive Surgery, Catholic University of Daegu) ;
  • Kim, Sung-Eun (Department of Plastic and Reconstructive Surgery, Catholic University of Daegu) ;
  • Kim, Young Ah (Department of Pathology, School of Medicine, Catholic University of Daegu) ;
  • Choi, Hye Ryeon (Department of Surgery, Yonsei University College of Medicine)
  • 투고 : 2019.09.05
  • 심사 : 2019.10.30
  • 발행 : 2020.01.15

초록

Extramammary Paget disease (EMPD) is an uncommon malignancy that occurs in apocrine gland-rich areas of the body. EMPD of the axilla is rare, but a few cases have been reported. Some cases of EMPD have been reported with underlying apocrine adenocarcinoma; rarely, mammary-type ductal carcinoma can accompany EMPD. Here, we report a very rare case of EMPD with apocrine adenocarcinoma and invasive mammary-type ductal carcinoma. A 55-year-old woman was referred with a brownish pigmented plaque accompanying an area of ulceration in the left axilla. A preoperative biopsy indicated Paget disease, and an additional evaluation was performed to determine whether it was of primary or secondary origin. A wide excision was made, and the axilla was reconstructed using a thoracodorsal artery perforator flap. The biopsy showed apocrine adenocarcinoma and invasive mammary-type ductal carcinoma with pagetoid spreading. The patient had no evidence of recurrence or other postoperative complications.

키워드

참고문헌

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피인용 문헌

  1. Atypical cells on reflectance confocal microscopy may not represent melanoma: A case of axillary pigmented extramammary Paget disease vol.47, pp.12, 2020, https://doi.org/10.1111/cup.13804