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Factors Affecting the Duration of Untreated Psychosis in Community-Dwelling Patients with Schizophrenia Spectrum Disorder

지역사회 거주 조현병 범주 장애 환자의 정신증 미치료 기간 관련 요인

  • Kim, Mina (Gwangju Mental Health and Welfare Commission) ;
  • Kim, Jae-Kyeong (MindLink, Gwangju Bukgu Community Mental Health Center) ;
  • Jhon, Min (Department of Psychiatry, Chonnam National University Medical School) ;
  • Kim, Ju-Wan (Department of Psychiatry, Chonnam National University Medical School) ;
  • Lee, Ju-Yeon (Gwangju Mental Health and Welfare Commission) ;
  • Kim, Jae-Min (Department of Psychiatry, Chonnam National University Medical School) ;
  • Shin, IL-Seon (Department of Psychiatry, Chonnam National University Medical School) ;
  • Yoon, Jin-Sang (Department of Psychiatry, Chonnam National University Medical School) ;
  • Lee, Myung-Soo (GyeongGi-Do Mental Health and Welfare Center) ;
  • Kim, Sung-Wan (Gwangju Mental Health and Welfare Commission)
  • 김미나 (광주정신건강복지사업지원단) ;
  • 김재경 (마인드링크, 광주북구정신건강복지센터) ;
  • 전민 (전남대학교 의과대학 정신건강의학교실) ;
  • 김주완 (전남대학교 의과대학 정신건강의학교실) ;
  • 이주연 (광주정신건강복지사업지원단) ;
  • 김재민 (전남대학교 의과대학 정신건강의학교실) ;
  • 신일선 (전남대학교 의과대학 정신건강의학교실) ;
  • 윤진상 (전남대학교 의과대학 정신건강의학교실) ;
  • 이명수 (경기도정신건강복지센터) ;
  • 김성완 (광주정신건강복지사업지원단)
  • Received : 2019.09.17
  • Accepted : 2019.12.16
  • Published : 2020.04.30

Abstract

Objectives: This study aimed to identify factors affecting the duration of untreated psychosis (DUP) in patients with schizophrenia spectrum disorder. Methods: Six-hundred patients with schizophrenia spectrum disorder were recruited from mental health welfare centers in Gwangju Metropolitan City and Gyeonggi-do. Subjects were categorized into two groups according to median DUP. Demographic and clinical characteristics were compared between the two groups. Results: The mean DUP was 80.8 weeks, and the median DUP was 15.9 weeks. Patients with Medicaid, higher age, and longer duration of the schizophrenia prodrome were more likely to have a longer DUP. The DUP was shorter in patients who were consulted by family/relatives prior to treatment. Patients visiting university hospitals were more likely to have a shorter DUP compared with those visiting psychiatric clinics or small-sized mental hospitals, i.e., with less than 100 beds. A multivariate regression analysis showed that the duration of the prodrome was a factor that significantly affected DUP. Conclusion: The vulnerable group of patients with schizophrenia with a long DUP should be monitored closely. Moreover, it is necessary to develop a strategy to identify patients who have an insidious course of psychosis to reduce the DUP.

Keywords

Acknowledgement

연구 자료 수집에 도움을 주신 광주광역시와 경기도 지역의 정신 건강복지센터 선생님께 감사드립니다.

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