Journal of Korean Biological Nursing Science

Korean society of Biological Nursing Science (한국기초간호학회)
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Effect of Aerobic Exercise on Serum Lipids, Weight and Body Mass Index in Patients with Hypertension: A Systematic Review and Meta-analysis

유산소 운동이 고혈압 환자의 혈중지질, 체중 및 체질량지수에 미치는 효과: 체계적 문헌고찰 및 메타분석

  • Received : 2019.12.31
  • Accepted : 2020.02.12
  • Published : 2020.02.29
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Abstract

Purpose: The purpose of this study was to evaluate the effect of aerobic exercise on serum lipids, body weight, and body mass index in adults with hypertension using a systematic review and meta-analysis. Methods: Six electronic databases (PubMed, EMBASE, Co-chrane library, CINAHL, PsycINFO, SPORTDiscus) and five domestic databases were searched for randomized controlled trials studies. We used random effect models to derive weighted mean differences (WMD) and their 95% confidence intervals (CI) of aerobic exercise on serum lipids, body weight, and body mass index. Results: Nineteen studies met our inclusion criteria. In comparison with the control group, triglyceride level (TG) (-13.49 mg/dL, 95% CI: -26.74 to -0.24) and body weight (-0.62 kg, 95% CI: -1.08 to -0.16) difference between follow-up and baseline was significantly reduced in the aerobic exercise group. However, no difference was found in total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and body mass index (BMI). Conclusion: Aerobic exercise is effective in reducing the TG level and body weight in adults with hypertension. In order to improve levels of serum TC, LDL-C and HDL-C of hypertensive patients, it's needed to combine other intervention methods such as diet therapy.

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References

  1. Jung KH. 2017 National survey of older Koreans. Final repor. Sejong: Korea Institute for Health and Social Affairs; 2018. Report No.: Policy Report 2018-01.
  2. Weber MA, Schiffrin EL, White WB, Samuel M, Lindholm LH, Kenerson JG, et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. The Journal of Clinical Hypertension. 2014;32(1):3-15. https://doi.org/10.1111/jch.12237
  3. The Korean Society of Hypertension. The guidelines of treatment of hypertension 2018. Seoul: The Korean Society of Hypertension; 2018 [cited 2019 Dec 1]. Available from: http://www.koreanhypertension.org/reference/guide?mode= read&idno=4246.
  4. Ates I, Ozkayar N, Ates H, Karakulak UN, Kursun O, Topcuoglu C, et al. Elevated circulating sST2 associated with subclinical atherosclerosis in newly diagnosed primary hypertension. Hypertension Research. 2016;39(7):513-518. https://doi.org/10.1038/hr.2016.16
  5. Halperin RO, Sesso HD, Ma J, Buring JE, Stampfer MJ, Gaziano JM. Dyslipidemia and the risk of incident hypertension in men. Hypertension, 2006;47(1): 45-50. https://doi.org/10.1161/01.HYP.0000196306.42418.0e
  6. Lewington S, Whitlock G, Clarke R, Sherliker P, Emberson J, Halsey J, et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. The Lancet. 2007;370(9602):1829-1839. https://doi.org/10.1016/S0140-6736(07)61778-4
  7. Aydin E, Ates I, Arikan MF, Yilmaz N, Dede F. The ratio of monocyte frequency to HDL cholesterol level as a predictor of asymptomatic organ damage in patients with primary hypertension. Hypertension Research. 2017;40(8):758-764. https://doi.org/10.1038/hr.2017.36
  8. Kim JW, Park CH, Kim TU. Effects of 12 weeks walking on metabolic syndrome markers, growth hormone and IGF-I in obese girls. The Korean Journal of Growth and Development. 2008;16(1):9-17.
  9. Lee CJ, Ko YH, Shin DS. Effect of combined treatment of aerobic exercise and resistance exercise on blood lipids and C-reactive protein in hypertensive patients. Korean Journal of Sports Science. 2014;23(1):1077-1087.
  10. Cook Z, Kirt S, Lawrenson S, Sandford S. Use of BMI in the assessement of undernutrition in older subject: reflecting on practice. Proceeding of the Nutrition Society. 2005;64(3):313-317. https://doi.org/10.1079/PNS2005437
  11. Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. Journal of the American College of Cardiology. 2009;53(21):1925-1932. https://doi.org/10.1016/j.jacc.2008.12.068
  12. Safar ME, Czernichow S, Blacher J. Obesity, arterial stiffness, and cardiovascular risk. Journal of the American Society of Nephrology. 2006;17(4 Suppl 2):S109-S111. https://doi.org/10.1681/ASN.2005121321
  13. Jensen MD, Ryan DH, Aprovian CM, Ard JD, Comuzzie AG, Donato KA, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Journal of the American College of Cardiology. 2014;63(25):2985-3023. https://doi.org/10.1016/j.jacc.2013.11.004
  14. Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. International Journal of Surgery. 2010;8(5):336-341. https://doi.org/10.1016/j.ijsu.2010.02.007
  15. Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomized trials. British Medical Journal. 2019;366:l4898. https://doi.org/10.1136/bmj.l4898
  16. Kim SY, Park JE, Seo HJ, Lee YJ, Son HJ, Jang BH, et al. NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. Seoul: National Evidence-based Healthcare collaborating Agency; 2011. p. 1-165.
  17. Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.1.0 [Internet]. London: The Cochrane Collaboration; 2011 [cited 2019 Dec 1]. Available from: http://handbook-5-1.cochrane.org/.
  18. Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta analysis. Journal of the American Heart Association. 2013; 2(1):1-9. https://doi.org/10.1161/JAHA.112.004473
  19. Borjesson M, Onerup A, Lundqvist S, Dahlof B. Physical activity and exercise lower blood pressure in individuals with hypertension: narrative review of 27 RCTs. British Journal of Sports Medicine. 2016;50(6):356-361. https://doi.org/10.1136/bjsports-2015-095786
  20. Son JU, Lee JH. The effect of the walking exercise on physiological index, physical fitness, self esteem, depression and life satisfaction in the institutionalized elderly women. Journal of Korean Academy of Community Health Nursing. 2006;17(1):5-16.
  21. Riebe D, Ehrman JK, Liguori G, Magal M. ACSM's guidelines for exercise testing and prescription. 10th ed. Kim WS. et al. translator. Indianapolis, IN: Wolters kluwer Health Inc.; 2018. 224-234.
  22. Sarzynski MA, Burton J, Rankinen T, Blair SN, Church TS, Despres JP, et al. The effects of exercise on the lipoprotein subclass profile: a meta-analysis is 10 interventions. Atherosclerosis. 2015;243(2):364-372. https://doi.org/10.1016/j.atherosclerosis.2015.10.018
  23. Kelley GA, Kelley KS, Roberts S, Haskell W. Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials. Clinical Nutrition. 2012;31(2):156-167. https://doi.org/10.1016/j.clnu.2011.11.011
  24. Lee HS. The effects of aerobic exercise for body composition, serum lipids, self-efficacy and life satisfaction in middle-aged women. Korean Journal of Health Promotion. 2007;7(3):196-204.
  25. Farrel SW, Finley CE, Grundy SM. Cardiorespiratory fitness, LDL cholesterol, and CHD mortality in men. Medicine & Science in Sport & Exercise. 2012; 44(11):2132-2137. https://doi.org/10.1249/MSS.0b013e31826524be
  26. Mann S, Beedie C, Jimenez A. Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Medicine. 2014;44(2):211-221. https://doi.org/10.1007/s40279-013-0110-5
  27. Wu T, Gao X, Chen M, Da V. Long-term effectiveness of diet-plus exercise interventions vs. diet-only interventions for weight loss: a meta-analysis. Obesity Review 2009;10(3):313-323. https://doi.org/10.1111/j.1467-789X.2008.00547.x
  28. Pedersen BK, Saltin B. Exercise as medicine-evidence for prescribing exercise as therapy in 26 different chronic disease. Scandinavian Journal of Medicine & Science in Sport. 2015;25(S3):1-72. https://doi.org/10.1111/sms.12581
  29. Igarashi Y, Nogami Y. The effect of regular aquatic exercise on blood pressure: a meta-analysis of randomized controlled trials. European Journal of Preventive Cardiology. 2018;25(2):190-199. http://doi.org/10.1177/2047487317731164
  30. Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Annals of Internal Medicine. 2002;136(7):493-503. https://doi.org/10.7326/0003-4819-136-7-200204020-00006
  31. Park SH, Kim CG. Impact of resistance training on obesity index, lipid index, blood pressure, pulse rate, and bone mineral densitometer in middle-aged women: a meta-analysis of randomized controlled trials. The Korean Journal of Rehabilitation Nursing. 2019;22(1):1-14. https://doi.org/10.7587/kjrehn.2019.1
  32. Yang YJ. Evidence based exercise to control weight. Journal of the Korean Medical Association. 2017;60(10):806-816. https://doi.org/10.5124/jkma.2017.60.10.806