한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제37권2호
  • /
  • Pages.88-90
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  • 2020
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  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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Acquired Portosystemic Shunts Secondary to Hepatic Microvascular Dysplasia in a Young Dog

  • Hwang, Taesung (Institute of Animal Medicine, Department of Veterinary Medical Imaging, Collage of Veterinary Medicine, Gyeongsang National University) ;
  • An, Soyon (Institute of Animal Medicine, Department of Veterinary Medical Imaging, Collage of Veterinary Medicine, Gyeongsang National University) ;
  • Kim, Ahreum (Institute of Animal Medicine, Department of Veterinary Medical Imaging, Collage of Veterinary Medicine, Gyeongsang National University) ;
  • Han, Changhee (Institute of Animal Medicine, Department of Veterinary Medical Imaging, Collage of Veterinary Medicine, Gyeongsang National University) ;
  • Huh, Chan (Yangsan S animal Medical Center) ;
  • Lee, Hee Chun (Institute of Animal Medicine, Department of Veterinary Medical Imaging, Collage of Veterinary Medicine, Gyeongsang National University)
  • 투고 : 2020.02.25
  • 심사 : 2020.04.01
  • 발행 : 2020.04.30
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초록

A one year old spayed female Bichon Frise dog presented with gait abnormalities and seizure. Serum biochemical results showed elevated levels of alkaline phosphatase, alanine aminotransferase, and ammonia. Serum bile acid level was also increased to be over 30 μmol/L on preprandial. Urinalysis identified the presence of ammonium urate crystal. Abdominal ultrasonography and CT revealed aberrant, tortuous, and multiple small vessels connected to the caudal vena cava between left kidney and caudal vena cava. Macroscopic specific findings associated with extrahepatic congenital portosystemic shunts (PSS) or other liver diseases were not identified. Liver biopsy was performed. Histopathologic evaluation revealed hepatic lobular hypoplasia with portal arterial duplication and vascular shunts. Based on these finding, this case was diagnosed as multiple acquired PSS secondary to hepatic microvascular dysplasia (HMD) and hepatic encephalopathy. A liver biopsy is recommended to differentiate HMD from other liver diseases and to confirm HMD when a young dog has multiple acquired PSS.

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참고문헌

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