Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Histopathologic Characteristics of Canine Desmoplastic Melanoma

  • Chaudhary, Preeti Kumari (Department of Veterinary Medicine and Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University) ;
  • Chae, Yeon (Department of Veterinary Medicine and Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University) ;
  • Kim, Soochong (Department of Veterinary Medicine and Veterinary Medical Center, College of Veterinary Medicine, Chungbuk National University)
  • Received : 2019.12.25
  • Accepted : 2020.01.24
  • Published : 2020.02.28
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Abstract

An 11-year-old castrated male miniature Schnauzer, weighing 8 kg, presented with multiple masses on the humeri. Grossly, the masses were separated from the surrounding soft tissues. Desmoplastic melanoma is an uncommon tumor in dogs. Fine-needle aspiration cytology showed large spindle-shaped cells with a high nuclear-cytoplasmic ratio. Histopathology showed interlacing bundles of fibroblast-like cells, highly pleomorphic multinuclear cells, occasional atypical spindle cells separated by fibrocollagenous stroma, and lymphocyte aggregates admixed with abundant collagen. The tumors were diffusely positive for S100a, a strong marker for desmoplastic melanoma, and negative for desmin. Herein, we report the pathobiology of a rare, uncommon variant of melanoma in a dog.

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References

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