Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Radiography and ct features of atherosclerosis in two miniature schnauzer dogs

  • Lee, Eunji (College of Veterinary Medicine, Chonnam National University) ;
  • Kim, Hyun Woo (College of Veterinary Medicine, Chonnam National University) ;
  • Bae, Hyeona (College of Veterinary Medicine, Gyeongsang National University) ;
  • Yu, DoHyeon (College of Veterinary Medicine, Gyeongsang National University) ;
  • Choi, Jihye (College of Veterinary Medicine, Chonnam National University)
  • Received : 2020.08.20
  • Accepted : 2020.09.28
  • Published : 2020.11.30
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Abstract

Two miniature Schnauzer dogs with chronic pancreatitis were investigated. Both dogs showed systemic hypertension and increased concentrations of triglycerides and C-reactive protein. Abdominal radiography revealed cylindrical calcification in the retroperitoneum, and computed tomography (CT) showed extensive calcification of the abdominal and peripheral arteries in both dogs. Metastases and other dystrophic conditions that can cause arterial calcification were excluded based on the laboratory tests, and the dogs were diagnosed with atherosclerosis ante mortem. Atherosclerosis should be considered when extensive arterial calcification is observed on abdominal radiography or CT in miniature Schnauzers.

Keywords

Acknowledgement

This research was supported by the Animal Medical Institute of Chonnam National University and Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT, and Future Planning (NRF-2018R1A2B6006775 and NRF-2020R1C1C1008675).

References

  1. Kagawa Y, Hirayama K, Uchida E, Izumisawa Y, Yamaguchi M, Kotani T, et al. Systemic atherosclerosis in dogs: histopathological and immunohistochemical studies of atherosclerotic lesions. J Comp Pathol. 1998;118(3):195-206. https://doi.org/10.1016/S0021-9975(05)80126-4
  2. Wang Y, Osborne MT, Tung B, Li M, Li Y. Imaging cardiovascular calcification. J Am Heart Assoc. 2018;7(13):1-15.
  3. Drost WT, Bahr RJ, Henry GA, Campbell GA. Aortoiliac thrombus secondary to a mineralized arteriosclerotic lesion. Vet Radiol Ultrasound. 1999;40(3):262-266. https://doi.org/10.1111/j.1740-8261.1999.tb00359.x
  4. Lefbom BK, Adams WH, Weddle DL. Mineralized arteriosclerosis in a cat. Vet Radiol Ultrasound. 1996;37(6):420-423. https://doi.org/10.1111/j.1740-8261.1996.tb01253.x
  5. Guimaraes Henriques JC, Kreich EM, Helena Baldani M, Luciano M, Cezar de Melo Castilho J, Cesar de Moraes L. Panoramic radiography in the diagnosis of carotid artery atheromas and the associated risk factors. Open Dent J. 2011;5(1):79-83. https://doi.org/10.2174/1874210601105010079
  6. Kobayashi K, Ando K, Seki T, Hamada T, Suzuki K, Ishiguro N, et al. Carotid artery plaque screening using abdominal aortic calcification on lumbar radiographs. PLoS One. 2019;14(1):e0209175. https://doi.org/10.1371/journal.pone.0209175
  7. Ibanez B, Badimon JJ, Garcia MJ. Diagnosis of atherosclerosis by imaging. Am J Med. 2009;122(1 Suppl):S15-S25. https://doi.org/10.1016/j.amjmed.2008.10.014
  8. Joshi FR, Lindsay AC, Obaid DR, Falk E, Rudd JH. Non-invasive imaging of atherosclerosis. Eur Heart J Cardiovasc Imaging. 2012;13(3):205-218. https://doi.org/10.1093/ehjci/jer319
  9. Tarkin JM, Dweck MR, Evans NR, Takx RA, Brown AJ, Tawakol A, et al. Imaging therosclerosis. Circ Res. 2016;118(4):750-769. https://doi.org/10.1161/CIRCRESAHA.115.306247
  10. Liu SK, Tilley LP, Tappe JP, Fox PR. Clinical and pathologic findings in dogs with atherosclerosis: 21 cases (1970-1983). J Am Vet Med Assoc 1986;189(2):227-232. PUBMED
  11. Hess RS, Kass PH, Van Winkle TJ. Association between diabetes mellitus, hypothyroidism or hyperadrenocorticism, and atherosclerosis in dogs. J Vet Intern Med. 2003;17(4):489-494. https://doi.org/10.1892/0891-6640(2003)017<0489:ABDMHO>2.3.CO;2
  12. Wong VM, Kidney BA, Snead EC, Myers SL, Jackson ML. Serum C-reactive protein concentrations in healthy miniature Schnauzer dogs. Vet Clin Pathol. 2011;40(3):380-383. https://doi.org/10.1111/j.1939-165X.2011.00336.x
  13. Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am J Pathol. 2001;158(3):1039-1051. https://doi.org/10.1016/s0002-9440(10)64051-5
  14. Benzaquen LR, Yu H, Rifai N. High sensitivity C-reactive protein: an emerging role in cardiovascular risk assessment. Crit Rev Clin Lab Sci. 2002;39(4-5):459-497. https://doi.org/10.1080/10408360290795556
  15. Teramoto T, Sasaki J, Ishibashi S, Birou S, Daida H, Dohi S, et al. Executive summary of the Japan Atherosclerosis Society (JAS) guidelines for the diagnosis and prevention of atherosclerotic cardiovascular diseases in Japan-2012 version. J Atheroscler Thromb. 2013;20(6):517-523. https://doi.org/10.5551/jat.15792