Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Assessment of hemagglutination activity of porcine deltacoronavirus

  • Zhang, Yunfei (College of Animal Science and Veterinary Medicine, Henan Agricultural University) ;
  • Han, Li (College of Animal Science and Veterinary Medicine, Henan Agricultural University) ;
  • Xia, Lu (College of Animal Science and Veterinary Medicine, Henan Agricultural University) ;
  • Yuan, Yixin (College of Animal Science and Veterinary Medicine, Henan Agricultural University) ;
  • Hu, Hui (College of Animal Science and Veterinary Medicine, Henan Agricultural University)
  • Received : 2019.07.16
  • Accepted : 2019.10.23
  • Published : 2020.01.31
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Abstract

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated. Our results showed that PDCoV has the ability to agglutinate rabbit erythrocytes after virion pretreatment with trypsin or neuraminidase. Additionally, the HA assay results showed a significant positive correlation with the infectious viral titer. Our results suggest that assessing the HA activity of PDCoV may be a useful diagnostic method for investigating and surveilling PDCoV infections.

Keywords

Acknowledgement

This study was supported by funds from the National Key Research and Development Program of China (2016YFD0500102-1 and 2018YFD0500100) and the National Natural Science Foundation of China (No. 31772773 and U1704231).

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