Journal of Veterinary Science

  • 제21권3호
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  • Pages.40.1-40.8
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  • 2020
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  • 1229-845X(pISSN)
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  • 1976-555X(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
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High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals

  • Sum, Samuth (Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine) ;
  • Oh, Jae Young (Department of Veterinary Internal Medicine, Konkuk University College of Veterinary Medicine)
  • 투고 : 2019.11.06
  • 심사 : 2020.02.28
  • 발행 : 2020.05.31
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초록

The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future.

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과제정보

This research was supported by funding (Grant No. 2017ER5405-02) from the Research of Korea Centers for Disease Control and Prevention.

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