참고문헌
- Nishtar S, Gluckman P, Armstrong T. Ending childhood obesity: a time for action. Lancet 2016;387:825-7. https://doi.org/10.1016/S0140-6736(16)00140-9
- Indonesia. Badan Penelitian dan Pengembangan Kesehatan. Riset kesehatan dasar: riskesdas, 2013. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan RI, 2013.
- Kementerian Kesehatan; Badan Penelitian dan Pengembangan Kesehatan. Hasil utama RISKESDAS 2018. Jakarta: Kementerian Kesehatan Republik indonesia, 2018.
- Kloting N, Bluher M. Adipocyte dysfunction, inflammation and metabolic syndrome. Rev Endocr Metab Disord 2014;15:277-87. https://doi.org/10.1007/s11154-014-9301-0
- Harris RB. Direct and indirect effects of leptin on adipocyte metabolism. Biochim Biophys Acta 2014;1842:414-23. https://doi.org/10.1016/j.bbadis.2013.05.009
- Elias CF. Leptin action in pubertal development: recent advances and unanswered questions. Trends Endocrinol Metab 2012;23:9-15. https://doi.org/10.1016/j.tem.2011.09.002
- Kennedy A, Gettys TW, Watson P, Wallace P, Ganaway E, Pan Q, et al. The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure. J Clin Endocrinol Metab 1997;82:1293-300. https://doi.org/10.1210/jcem.82.4.3859
- Kavazarakis E, Moustaki M, Gourgiotis D, Drakatos A, Bossios A, Zeis PM, et al. Relation of serum leptin levels to lipid profile in healthy children. Metabolism 2001;50:1091-4. https://doi.org/10.1053/meta.2001.25606
- Chan JL, Bluher S, Yiannakouris N, Suchard MA, Kratzsch J, Mantzoros CS. Regulation of circulating soluble leptin receptor levels by gender, adiposity, sex steroids, and leptin: observational and interventional studies in humans. Diabetes 2002;51:2105-12. https://doi.org/10.2337/diabetes.51.7.2105
- Kratzsch J, Lammert A, Bottner A, Seidel B, Mueller G, Thiery J, et al. Circulating soluble leptin receptor and free leptin index during childhood, puberty, and adolescence. J Clin Endocrinol Metab 2002;87:4587-94. https://doi.org/10.1210/jc.2002-020001
- Hill RA, Margetic S, Pegg GG, Gazzola C. Leptin: its pharmacokinetics and tissue distribution. Int J Obes Relat Metab Disord 1998;22:765-70. https://doi.org/10.1038/sj.ijo.0800656
- Shalitin S, Phillip M. Role of obesity and leptin in the pubertal process and pubertal growth--a review. Int J Obes Relat Metab Disord 2003;27:869-74. https://doi.org/10.1038/sj.ijo.0802328
- Barlow SEExpert Committee. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007;120 Suppl 4:S164-92. https://doi.org/10.1542/peds.2007-2329C
- Sjarif DR, Nasar SS, Devaera Y, Tanjung CF. Asuhan nutrisi pediatrik. Jakarta: Ikatan Dokter Anak Indonesia, 2011.
- Harrell FE. Regression modeling strategies: with applications to linear models, logistic regression and survival analysis. New York: Springer, 2001:53-85.
- Austin PC, Steyerberg EW. The number of subjects per variable required in linear regression analyses. J Clin Epidemiol 2015;68:627-36. https://doi.org/10.1016/j.jclinepi.2014.12.014
- TANITA. Tanita BC-545n: your digital personal trainer [Internet]. Tokyo: TANITA; date unknown [cited 2019 Jul 31]. Available from: https://tanita.eu/products/body-composition-monitors/bc-545n
- NutriSurvey. Nutrition surveys and calculations [Internet]. Geneva: NutriSurvey; 2010 [cited 2019 Jul 31]. Available from: http://www.nutrisurvey.de/index.html
- Majid H, Masood Q, Khan AH. Homeostatic model assessment for insulin resistance (HOMA-IR): a better marker for evaluating insulin resistance than fasting insulin in women with polycystic ovarian syndrome. J Coll Physicians Surg Pak 2017;27:123-6.
- R&D Systems. ELISAs and ELISA Kits [Internet]. Minneapolis: R&D Systems, date unknown [cited 2019 Jul 31]. Available from: https://www.rndsystems.com/products/elisas
- Pandit R, Beerens S, Adan RAH. Role of leptin in energy expenditure: the hypothalamic perspective. Am J Physiol Regul Integr Comp Physiol 2017;312:R938-47. https://doi.org/10.1152/ajpregu.00045.2016
- Brydon L. Adiposity, leptin and stress reactivity in humans. Biol Psychol 2011;86:114-20. https://doi.org/10.1016/j.biopsycho.2010.02.010
- Maamra M, Bidlingmaier M, Postel-Vinay MC, Wu Z, Strasburger CJ, Ross RJ. Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors. Endocrinology 2001;142:4389-93. https://doi.org/10.1210/en.142.10.4389
- Myers MG Jr, Heymsfield SB, Haft C, Kahn BB, Laughlin M, Leibel RL, et al. Challenges and opportunities of defining clinical leptin resistance. Cell Metab 2012;15:150-6. https://doi.org/10.1016/j.cmet.2012.01.002
- Sainz N, Barrenetxe J, Moreno-Aliaga MJ, Martinez JA. Leptin resistance and diet-induced obesity: central and peripheral actions of leptin. Metabolism 2015;64:35-46. https://doi.org/10.1016/j.metabol.2014.10.015
- Silha JV, Krsek M, Skrha JV, Sucharda P, Nyomba BL, Murphy LJ. Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance. Eur J Endocrinol 2003;149:331-5. https://doi.org/10.1530/eje.0.1490331
- Brabant G, Horn R, von zur Muhlen A, Mayr B, Wurster U, Heidenreich F, et al. Free and protein bound leptin are distinct and independently controlled factors in energy regulation. Diabetologia 2000;43:438-42. https://doi.org/10.1007/s001250051326
- Yannakoulia M, Yiannakouris N, Bluher S, Matalas AL, Klimis-Zacas D, Mantzoros CS. Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrinol Metab 2003;88:1730-6. https://doi.org/10.1210/jc.2002-021604
- Izadi V, Saraf-Bank S, Azadbakht L. Dietary intakes and leptin concentrations. ARYA Atheroscler 2014;10:266-72.
- Weigle DS, Cummings DE, Newby PD, Breen PA, Frayo RS, Matthys CC, et al. Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet. J Clin Endocrinol Metab 2003;88:1577-86. https://doi.org/10.1210/jc.2002-021262
- Kong A, Neuhouser ML, Xiao L, Ulrich CM, McTiernan A, Foster-Schubert KE. Higher habitual intake of dietary fat and carbohydrates are associated with lower leptin and higher ghrelin concentrations in overweight and obese postmenopausal women with elevated insulin levels. Nutr Res 2009;29:768-76. https://doi.org/10.1016/j.nutres.2009.10.013
- Romon M, Lebel P, Velly C, Marecaux N, Fruchart JC, Dallongeville J. Leptin response to carbohydrate or fat meal and association with subsequent satiety and energy intake. Am J Physiol 1999;277:E855-61.
- Giovannucci E, Pollak M, Liu Y, Platz EA, Majeed N, Rimm EB, et al. Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men. Cancer Epidemiol Biomarkers Prev 2003;12:84-9.
- Rostami H, Samadi M, Yuzbashian E, Zarkesh M, Asghari G, Hedayati M, et al. Habitual dietary intake of fatty acids are associated with leptin gene expression in subcutaneous and visceral adipose tissue of patients without diabetes. Prostaglandins Leukot Essent Fatty Acids 2017;126:49-54. https://doi.org/10.1016/j.plefa.2017.09.010
- UKK Nutrisi dan penyakit metabolik; Ikatan dokter anak Indonesia. Diagnosis, tata laksana dan pencegahan obesitas pada anak dan remaja. Jakarta: Ikatan Dokter Anak Indonesia; 2014.
- Mohan V, Ruchi V, Gayathri R, Bai MR, Sudha V, Anjana RM, et al. Slowing the diabetes epidemic in the World Health Organization South-East Asia Region: the role of diet and physical activity. WHO South- East Asia J Public Health 2016;5:5-16. https://doi.org/10.4103/2224-3151.206554
- Haluzik M, Fiedler J, Nedvidkova J, Ceska R. Serum leptin concentrations in patients with combined hyperlipidemia: relationship to serum lipids and lipoproteins. Physiol Res 1999;48:363-8.
- Haluzik M, Fiedler J, Nedvidkova J, Ceska R. Serum leptin levels in patients with hyperlipidemias. Nutrition 2000;16:429-33. https://doi.org/10.1016/S0899-9007(00)00288-4
- Slama FB, Jridi N, Rayana MCB, Trimeche A, Hsairi M, Belhadj O. Plasma levels of leptin and ghrelin and their correlation with BMI, and circulating lipids and glucose in obese Tunisian women. Asian Biomed 2015;9:161-8. https://doi.org/10.5372/1905-7415.0902.382
- Wu DM, Shen MH, Chu NF. Relationship between plasma leptin levels and lipid profiles among school children in Taiwan--the Taipei Children Heart Study. Eur J Epidemiol 2001;17:911-6. https://doi.org/10.1023/A:1016280427032
- Iglesias MJ, Eiras S, Pineiro R, Lopez-Otero D, Gallego R, Fernandez AL, et al. [Gender differences in adiponectin and leptin expression in epicardial and subcutaneous adipose tissue. Findings in patients undergoing cardiac surgery]. Rev Esp Cardiol 2006;59:1252-60. Spanish. https://doi.org/10.1016/S1885-5857(07)60081-4
- Obermann-Borst SA, Eilers PH, Tobi EW, de Jong FH, Slagboom PE, Heijmans BT, et al. Duration of breastfeeding and gender are associated with methylation of the LEPTIN gene in very young children. Pediatr Res 2013;74:344-9. https://doi.org/10.1038/pr.2013.95
- Maffeis C, Moghetti P, Vettor R, Lombardi AM, Vecchini S, Tato L. Leptin concentration in newborns' cord blood: relationship to gender and growth-regulating hormones. Int J Obes Relat Metab Disord 1999;23:943-7. https://doi.org/10.1038/sj.ijo.0801023
- Rutters F, Nieuwenhuizen AG, Verhoef SP, Lemmens SG, Vogels N, Westerterp-Plantenga MS. The relationship between leptin, gonadotropic hormones, and body composition during puberty in a Dutch children cohort. Eur J Endocrinol 2009;160:973-8. https://doi.org/10.1530/EJE-08-0762
- Fadoua G, de Leon AC, Ferid M, Mohsen S, Nebil A. Leptin, insulin and lipid profiles in obese subjects with and without metabolic syndrome in the region of Cap-Bon: Tunisia. Endocrinol Metab Synd 2015;4:1-6.
- Jazet IM, Pijl H, Meinders AE. Adipose tissue as an endocrine organ: impact on insulin resistance. Neth J Med 2003;61:194-212.
- Gonzaga NC, Medeiros CC, de Carvalho DF, Alves JG. Leptin and cardiometabolic risk factors in obese children and adolescents. J Paediatr Child Health 2014;50:707-12. https://doi.org/10.1111/jpc.12610
- Valle Jimenez M, Martos R, Morales RM, Valle R, Canete MD, Urbano MM, et al. Relationship between changes in plasma leptin concentrations and plasminogen activator inhibitor-1 in obese prepubertal children after nine months of treatment. Ann Nutr Metab 2013;63:216-22. https://doi.org/10.1159/000351597