DOI QR코드

DOI QR Code

Chylothorax after Surgery for Congenital Cardiac Disease: A Prevention and Management Protocol

  • Shin, Yu Rim (Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Lee, Ha (Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Park, Young-Hwan (Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Park, Han Ki (Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine)
  • Received : 2019.09.02
  • Accepted : 2019.10.22
  • Published : 2020.04.05

Abstract

Background: Chylothorax after congenital heart surgery is not an uncommon complication, and it is associated with significant morbidity. However, consensus treatment guidelines are lacking. To improve the treatment outcomes of patients with postoperative chylothorax, we implemented a standardized management protocol at Severance Hospital in September 2014. Methods: A retrospective review of patients treated at a single center was done. All corrective and palliative operations for congenital heart disease performed at our institution between January 2008 and April 2018 were reviewed. The incidence and treatment outcomes of postoperative chylothorax were analyzed. Results: The incidence of chylothorax was 1.9%. Sixty-one percent of the patients could be managed with a low-fat diet, while 28% of the patients required complete restriction of enteral feeding. Thoracic duct embolization was performed in 2 patients and chest tube drainage decreased immediately after the procedure. No patient required thoracic duct ligation or pleurodesis. After implementation of the institutional management protocol, the number of chest tube drainage days decreased (median, 24 vs. 14 days; p=0.45). Conclusion: Implementing a strategy to reduce postoperative chylothorax resulted in an acceptable incidence of postoperative chylothorax. Instituting a clinical practice protocol helped to curtail the treatment duration and to decrease the requirement for surgical treatment. Image-guided embolization of the thoracic duct is an effective treatment for postoperative chylothorax.

Keywords

References

  1. Milonakis M, Chatzis AC, Giannopoulos NM, et al. Etiology and management of chylothorax following pediatric heart surgery. J Card Surg 2009;24:369-73. https://doi.org/10.1111/j.1540-8191.2008.00781.x
  2. Bauman ME, Moher C, Bruce AK, Kuhle S, Kaur S, Massicotte MP. Chylothorax in children with congenital heart disease: incidence of thrombosis. Thromb Res 2013;132:e83-5. https://doi.org/10.1016/j.thromres.2013.06.014
  3. Mery CM, Moffett BS, Khan MS, et al. Incidence and treatment of chylothorax after cardiac surgery in children: analysis of a large multi-institution database. J Thorac Cardiovasc Surg 2014;147:678-86. https://doi.org/10.1016/j.jtcvs.2013.09.068
  4. Buckley JR, Graham EM, Gaies M, et al. Clinical epidemiology and centre variation in chylothorax rates after cardiac surgery in children: a report from the Pediatric Cardiac Critical Care Consortium. Cardiol Young 2017;27:1678-85. https://doi.org/10.1017/s104795111700097x
  5. Nath DS, Savla J, Khemani RG, Nussbaum DP, Greene CL, Wells WJ. Thoracic duct ligation for persistent chylothorax after pediatric cardiothoracic surgery. Ann Thorac Surg 2009;88:246-52. https://doi.org/10.1016/j.athoracsur.2009.03.083
  6. Aljazairi AS, Bhuiyan TA, Alwadai AH, Almehizia RA. Octreotide use in post-cardiac surgery chylothorax: a 12-year perspective. Asian Cardiovasc Thorac Ann 2017;25:6-12. https://doi.org/10.1177/0218492316682670
  7. Ok YJ, Kim YH, Park CS. Surgical reconstruction for high-output chylothorax associated with thrombo-occlusion of superior vena cava and left innominate vein in a neonate. Korean J Thorac Cardiovasc Surg 2018;51:202-4. https://doi.org/10.5090/kjtcs.2018.51.3.202
  8. Lee KH, Jung JS, Cho SB, Lee SH, Kim HJ, Son HS. Thoracic duct embolization with lipiodol for chylothorax due to thoracic endovascular aortic repair with debranching procedure. Korean J Thorac Cardiovasc Surg 2015;48:74-7. https://doi.org/10.5090/kjtcs.2015.48.1.74
  9. Hur S, Shin JH, Lee IJ, et al. Early experience in the management of postoperative lymphatic leakage using lipiodol lymphangiography and adjunctive glue embolization. J Vasc Interv Radiol 2016;27:1177-86. https://doi.org/10.1016/j.jvir.2016.05.011
  10. Savla JJ, Itkin M, Rossano JW, Dori Y. Post-operative chylothorax in patients with congenital heart disease. J Am Coll Cardiol 2017;69:2410-22.
  11. Borasino S, Diaz F, El Masri K, Dabal RJ, Alten JA. Central venous lines are a risk factor for chylothorax in infants after cardiac surgery. World J Pediatr Congenit Heart Surg 2014;5:522-6. https://doi.org/10.1177/2150135114550723
  12. Yeh J, Brown ER, Kellogg KA, et al. Utility of a clinical practice guideline in treatment of chylothorax in the postoperative congenital heart patient. Ann Thorac Surg 2013;96:930-6. https://doi.org/10.1016/j.athoracsur.2013.05.058
  13. Day TG, Zannino D, Golshevsky D, d'Udekem Y, Brizard C, Cheung MMH. Chylothorax following paediatric cardiac surgery: a case-control study. Cardiol Young 2018;28:222-8. https://doi.org/10.1017/S1047951117001731
  14. Winder MM, Eckhauser AW, Delgado-Corcoran C, Smout RJ, Marietta J, Bailly DK. A protocol to decrease postoperative chylous effusion duration in children. Cardiol Young 2018;28:816-25. https://doi.org/10.1017/S1047951118000392