대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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위식도역류질환의 한약 치료에 대한 최신 임상 연구 동향 - 반하(半夏)를 중심으로 -

Recent Trends in Clinical Research on Herbal Medicine Based on Pinellia Ternata for Treatment of Gastroesophageal Reflux Disease

  • 장혜연 (동신대학교 한의과대학 내과학교실) ;
  • 김영광 (동신대학교 한의과대학 내과학교실) ;
  • 정서윤 (동신대학교 한의과대학 한방신경정신과학교실) ;
  • 김도형 (동신대학교 한의과대학 한방재활의학과교실) ;
  • 김경옥 (동신대학교 한의과대학 한방신경정신과학교실) ;
  • 이영수 (동신대학교 한의과대학 내과학교실)
  • Jang, Hye-yeon (Dept. of Korean Internal Medicine, College of Korean Medicine, Dong-Shin University) ;
  • Kim, Young-kwang (Dept. of Korean Internal Medicine, College of Korean Medicine, Dong-Shin University) ;
  • Jeong, Seo-yun (Dept. of Neuropsychiatry and Pathology, College of Korean Medicine, Dong-Shin University) ;
  • Kim, Do-hyeong (Dept. of Rehabilitation Medicine of Korean Medicine, College of Korean Medicine, Dong-Shin University) ;
  • Kim, Kyeong-ok (Dept. of Neuropsychiatry and Pathology, College of Korean Medicine, Dong-Shin University) ;
  • Lee, Young-su (Dept. of Korean Internal Medicine, College of Korean Medicine, Dong-Shin University)
  • 투고 : 2020.11.28
  • 심사 : 2020.12.31
  • 발행 : 2020.12.30
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초록

Objective: The purpose of this study was to review Chinese clinical studies of the treatment of gastroesophageal reflux disease (GERD) with herbal medicine including Pinellia ternata. Methods: We searched the China National Knowledge Infrastructure (CNKI) database for clinical studies on herbal treatments including Pinellia ternata for GERD, from January 1st, 2015 to September 30th, 2019. We evaluated the risk of bias using Cochrane's risk of bias to confirm the quality of the 37 selected documents. Results: The 37 papers included high-dose and middle-dose Pinellia ternata groups. The outcome measures included treatment effectiveness rate, symptom comparisons, and endoscopy effectiveness rates or scores. In both groups, most studies showed significant improvement in the treatment group compared with the control group. The meta-analysis revealed a higher treatment effectiveness rate and a lower recurrence rate in the treatment group than in the control group. Conclusions: Comparing the treatment effect between the two groups was difficult due to the low quality of most studies. However, the results suggest that herbal remedies including Pinellia ternata showed statistically significant improvement in GERD compared to control groups.

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