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Validity Study of the Systemic Exertion Intolerance Disease Questionnaire (SEID-Q27) for Chronic Fatigue Syndrome (CFS) Diagnosis

SEID(Systemic Exertion Intolerance Disease) 진단 기준을 바탕으로 한 만성 피로 증후군 진단 설문지(SEID-Q27) 타당도 연구

  • Lim, Eun-jin (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University) ;
  • Son, Chang-gue (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University) ;
  • Jang, Eun-su (Institute of Bioscience and Integrative Medicine, Dept. of Oriental Medicine College, Daejeon University)
  • 임은진 (동서생명과학연구원 대전대학교 한의학과) ;
  • 손창규 (동서생명과학연구원 대전대학교 한의학과) ;
  • 장은수 (동서생명과학연구원 대전대학교 한의학과)
  • Received : 2020.10.28
  • Accepted : 2020.12.28
  • Published : 2020.12.30

Abstract

Purpose: This study assessed the validity of a questionnaire (SEID-Q27) for diagnosis of chronic fatigue syndrome (CFS), designed based on the systematic exertion intolerance disorder (SEID) criteria. Methods: Two groups of participants were recruited: 1. a non-CFS control group: adult university personnel with a Chalder fatigue scale (CFQ) score ≥15, and 2. a CFS patient group: patients from an online CFS community diagnosed with CFS (diagnostic code of G93.3) with the symptoms present. The survey ran from September to October, 2020. The validity of the questionnaire was investigated by factor analysis and receiver operator characteristic (ROC) analysis. Results: Among the 35 adults surveyed, 30 (86%) participants had CFQ scores ≥15 (15 males and 15 females) and 5 (14%) had a CFS diagnosis (2 males and 3 females). The total mean score was significantly different between the two groups (CFS: 6.8±2.2 vs. control: 4.4±2.4, p<0.05). The area under the curve (AUC) was 0.827. With a cut-off point 62, the sensitivity was 60%, specificity 97%, and the discriminant ability of the survey was 79%. Conclusions: The SEID -Q27 appears to be a useful instrument for the diagnosis of CFS using SEID criteria. However, further large-scale studies are needed with greater numbers of participants.

Keywords

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