Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Severe Case of Hypermagnesemia Caused by Ingesting Magnesium Containing Fertilizer

마그네슘 포함 비료 음독 후 발생한 중증의 고마그네슐혈증의 1례

  • Lee, Ka-young (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Yu, Jin-young (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Cho, Nam-Jun (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Park, Samel (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Lee, Eun-young (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Gil, Hyo-Wook (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital)
  • 이가영 (순천향대학교 천안병원 내과) ;
  • 유진영 (순천향대학교 천안병원 내과) ;
  • 조남준 (순천향대학교 천안병원 내과) ;
  • 박삼엘 (순천향대학교 천안병원 내과) ;
  • 이은영 (순천향대학교 천안병원 내과) ;
  • 길효욱 (순천향대학교 천안병원 내과)
  • Received : 2020.10.26
  • Accepted : 2020.11.05
  • Published : 2020.12.31
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Abstract

Hypermagnesemia is a rare condition that is usually iatrogenic in patients with elderly or renal failure. Severe hypermagnesemia is uncommon in patients with a normal renal function. Symptoms due to hypermagnesemia can range from mild symptoms, such as nausea, to severe symptoms, such as cardiac and respiratory arrest. This paper describes a case of a 49-year-old woman who ingested a magnesium-containing fertilizer with normal renal function. Cardiac arrest occurred eight hours after poisoning. Electrocardiography changed from a narrow QRS to a wide QRS and then to a complete atrioventricular block. Her hemodynamic state was unstable. Continuous renal replacement therapy was performed to remove magnesium from the blood, with the subsequent resolution of arrhythmia and hemodynamic stabilization. This paper reviews the pathophysiologic effects of magnesium on the cardiovascular system, clinical manifestation, and treatment of hypermagnesemia.

Keywords

References

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