Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Risk Factors to Predict Acute Respiratory Failure in Patients with Acute Pesticide Poisoning

급성 농약 중독환자에서 호흡 부전 발생의 위험 인자

  • Cho, Nam-Jun (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Park, Samel (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Lee, Eun Young (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital) ;
  • Gil, Hyo-Wook (Department of Internal Medicine, Soonchunhyang University Cheonan Hospital)
  • 조남준 (순천향대학교 천안병원 내과) ;
  • 박삼엘 (순천향대학교 천안병원 내과) ;
  • 이은영 (순천향대학교 천안병원 내과) ;
  • 길효욱 (순천향대학교 천안병원 내과)
  • Received : 2020.05.29
  • Accepted : 2020.07.20
  • Published : 2020.12.31
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Abstract

Acute respiratory failure is an important risk factor for mortality in patients with acute pesticide poisoning. Therefore, it is necessary to investigate the risk factors to predict respiratory failure in these patients. This study retrospectively investigated the clinical features of respiratory failure among patients with acute pesticide poisoning requiring mechanical ventilation. This study included patients who were admitted with intentional poisoning by pesticide ingestion from January 2017 to December 2019. Paraquat intoxication was excluded. Among 469 patients with acute pesticide poisoning, 398 patients were enrolled in this study. The respiratory failure rate was 30.4%. The rate of respiratory failure according to the type of pesticide was carbamate (75.0%), organophosphate (52.6%), glufosinate (52.1%), glyphosate (23%), pyrethroid (8.9%), and others (17%). The mortality was 25.6% in the respiratory failure group. The risk factors for respiratory failure were old age, low body mass index, and ingestion of more than 300 mL. In conclusion, respiratory failure is a risk factor for mortality in pesticide poisoning. Old age, low body mass index, and ingestion of more than 300 mL are the risk factors for predicting respiratory failure.

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References

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