Parasites, Hosts and Diseases

  • 제58권5호
  • /
  • Pages.559-564
  • /
  • 2020
  • /
  • 2982-5164(pISSN)
  • /
  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
권호 표지
DOI QR코드

DOI QR Code

Epidemiological Characteristics of Rodents and Chiggers with Orientia Tsutsugamushi in the Republic of Korea

  • Park, Jung Wook (Division of Infectious Disease Investigation, Health and Environment Research Institute of Gwangju) ;
  • Yu, Dae Sung (Division of Animal Disease Control, Animal and Plant Quarantine Agency) ;
  • Lee, Gi Seong (Division of Infectious Disease Investigation, Health and Environment Research Institute of Gwangju) ;
  • Seo, Jin Jong (Division of Infectious Disease Investigation, Health and Environment Research Institute of Gwangju) ;
  • Chung, Jae Keun (Division of Infectious Disease Investigation, Health and Environment Research Institute of Gwangju) ;
  • Lee, Jae Il (Department of Veterinary Public Health, College of Veterinary Medicine, Chonnam National University)
  • 투고 : 2020.02.16
  • 심사 : 2020.09.26
  • 발행 : 2020.10.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A survey of rodents and chiggers associated with Orientia tsutsugamushi was conducted in a rural region of the Republic of Korea (Korea) between 2014 and 2018. Overall Apodemus agrarius 15.2% had the highest seropisitive for O. tsutsugamushi, followed by Myodes regulus 11.4%. Monthly risk factors using logistic regression analysis were not associated with O. tsutsugamushi infections in rodents. The overall prevalence rate of O. tsutsugamushi among chiggers was 0.3%. The chigger (Leptotrombidium scutellare) and monthly (October) risk factors were associated with O. tsutsugamushi human infections (P<0.05). Orientia tsutsugamushi infections are endemic in rodents in Korea and people, for example, soldiers who are active outdoors, must employ preventive measures, especially during October (P<0.05). When there are many reports of O. tsutsugamushi infections in Korea. The Boryong strain 85.7% (2/14) was the most common strain detected in chiggers, followed by the Shimokoshi 7.1% (1/14) and Karp 7.1% strains.

키워드

참고문헌

  1. Fedrow AL, Lehman ML, Kelly DJ, Mullins K, Maina AN, Stewart RL, Ge H, Jonh H, Jiang J, Richards AL. A review of scrub typhus (Orientia tsutsugamushi and related organisms): then, now and tomorrow. Trop Med Infect Dis 2018; 3: 8. https://doi.org/10.3390/tropicalmed3010008
  2. Xu G, Walker DH, Jupiter D, Melby PC, Arcari CM. A review of the global epidemiology of scrub typhus. Plos One Neg Trop Dis 2017; 11: e0006062. https://doi.org/10.1371/journal.pntd.0006062
  3. Korea Centers for Disease Control and Prevention. Disease Web Statistics System [Internet]; [cited 2018 January 1]. Available from: http://is.cdc.go.kr/dsta/index.jsp.
  4. Song HJ. Environmental survey on the vectors and hosts of tsutsugamushi disease in Jeonnam province, Korea. Korea J Vet Serv 2012; 35: 183-189. https://doi.org/10.7853/kjvs.2012.35.3.183
  5. Lee IY, Song HJ, Choi YJ, Shin SH, Choi NK, Kwon SH, Shin EH, Pack C, Kim HC, Klein TA, Park KH, Jang WJ. Larval chigger mites collected from small mammals in 3 provinces, Korea. Korean J Parasitol 2014; 52: 225-229. https://doi.org/10.3347/kjp.2014.52.2.225
  6. Lee SH, Lee YS, Lee IY, Lim JW, Shin HK, Yu JR, Sim S. Monthly occurrence of vectors and reservoir rodents of scrub typhus in an endemic area of Jeollanamdo, Korea. Korean J Parasitol 2012; 50: 327-331. https://doi.org/10.3347/kjp.2012.50.4.327
  7. Takhampunya R, Tippayachai B, Promsathaporn S, Leepitakrat S, Monkanna T, Schuster AL, Melendrez MC, Paris DH, Richards AL, Richardson JH. Characterization based on the 56-Kda type-specific antigen gene of Orientia tsutsugamushi genotypes isolated from Leptotrombidium mites and the rodent host post infection. Am J Trop Med Hyg 2014; 90: 139-146. https://doi.org/10.4269/ajtmh.13-0393
  8. Kim DM, Kim KY, Man HS, Kweon SS, Park NY, Ryu SY. Risk factors for human infection with Orientia tsutsugamushi: a case-control study in Korea. Clin Microbiol Infect 2017; 14: 174-177. https://doi.org/10.1111/j.1469-0691.2007.01901.x
  9. Wei Y, Luo L, Jing Q, Le X, Huang U, Xial X, liu L, Wu X, Yang Z. A city park as a potential epidemic site of scrub typhus: a casecontrol study of an outbreak in Guanzhou, China. Parasit Vectors 2014; 7: 513. https://doi.org/10.1186/s13071-014-0513-7
  10. Wei Y, Huang Y, Li X, Ma Y, Tao X, Wu X, Yang Z. Climate variability, animal reservoir and transmission of scrub typhus in southern China. PLoS Negl Trop Dis 2017; 11: e0005447. https://doi.org/10.1371/journal.pntd.0005447
  11. Ree HI, Chang WH, Kee SH, Lee IY, Jeon SH. Detection of Orientia tsutsugamushi DNA in individual trombiculids using polymerase chain reaction in Korea. Med Entomol Zool 1997; 48: 197-209. https://doi.org/10.7601/mez.48.197
  12. Ree HI. Fauna and key to the chigger mites of Korea (Acarina: Trombiculidae and Leeuwenhoekiidae). Korean J Sys Zool 1990; 6: 57-70.
  13. Park JW, Kim SH, Park DW, Jung SH, Park HJ, Seo MH, Song HJ, Lee JY, Kim DM, Kim CM, Gill BC, Jeong HJ, Lee JM, Ha DR, Kim ES, Chung JK. Molecular epidemiology of an Orientia tsutsugamushi gene encoding a 56-kDa type-specific antigen in chiggers, small mammals, patients from the Southwest region of Korea. Am J Trop Med Hyg 2018; 98: 616-624. https://doi.org/10.4269/ajtmh.17-0070
  14. Park JW, Chung JK, Kim SH, Cho SJ, Ha YD, Jung SH, Park HJ, Song HJ, Lee JY, Kim DM, Pyus Jah, Ha DR, Kim ES, Lee JI. Seroepidemiological survey of zoonotic disease in small mammals with PCR detection of Orientia tsutsugamushi in chiggers, Gwangju, Korea. Korean J Parasitol 2016; 54: 307-313. https://doi.org/10.3347/kjp.2016.54.3.307
  15. Kim HC, Lee IY, Chong SU, Richards Al, Gu SH, Song JW, Lee JS, Klein TA. Serosurveillance of scrub typhus in small mammals collected from military training sites near the DMZ, northern Gyeonggi-do, Korea, and analysis of the relative abundance of chiggers from mammals examined. Korean J Parasitol 2010; 48: 237-243. https://doi.org/10.3347/kjp.2010.48.3.237
  16. Lin PR, Tsai HP, Weng MH, Lin HC, Chen KC, Kuo MD, Tsui PY, Hung YW, Hsu HL, Liu WT. Field assessment of Orientia tsutsugamushi infection in small mammals and its association with the occurrence of human scrub typhus in Taiwan. Acta Trop 2014; 131: 117-123. https://doi.org/10.1016/j.actatropica.2013.11.029
  17. Min C, Guo H, Tang T, Wang C, Li X, Pan X, Tang J. Spring scrub typhus, people's Republic of China. Emerg Infect Dis 2006; 12: 1463-1465. https://doi.org/10.3201/eid1209.060257
  18. Teppawar R, Patii A, Chaudhari S, Shinde S, Kolte S, Bhoyar A, Gilche Vijay. Zoonotic importance of rodents and their vectors in relation to perpetuation of scrub typhus in population. J Entomol Zool 2019; 7: 60-64.
  19. Takhampunya R, Korkusol A, Promsathaporn S, Tippayachao B, Leepirakrat S, Richard AL, Davidson SA. Heterogeneity of Orientia tsutsugamushi genotypes in field-collected trombiculid mite from wild-caught small mammals in Thailand. PLoS Negl Trop Dis 2018; 12: e0006632. https://doi.org/10.1371/journal.pntd.0006632
  20. Chaisiri K, Cosson JF, Morand S. Infection of rodents by Orientia tsutsugamushi, the agent of scrub typhus, in relation to land use in Thailand. Trop Med Infect Dis 2017; 2: 53. https://doi.org/10.3390/tropicalmed2040053
  21. Elliott I, Pearson I, Dajal P, Thomas NV, Roberts T, Newton PN. Scrub typhus ecology: a systematic review of Orientia in vectors and hosts. Parasit Vectors 2019; 12: 513. https://doi.org/10.1186/s13071-019-3751-x

피인용 문헌

  1. Nationwide Incidence of Chigger Mite Populations and Molecular Detection of Orientia tsutsugamushi in the Republic of Korea, 2020 vol.9, pp.8, 2020, https://doi.org/10.3390/microorganisms9081563
  2. Geographical Distribution and Epidemiologic Factors of Chigger Mites on Apodemus agrarius during Autumn in Korea vol.59, pp.5, 2021, https://doi.org/10.3347/kjp.2021.59.5.473