Maxillofacial Plastic and Reconstructive Surgery

  • Volume 41
  • /
  • Pages.39.1-39.6
  • /
  • 2019
  • /
  • 2288-8101(pISSN)
  • /
  • 2288-8586(eISSN)
Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지
DOI QR코드

DOI QR Code

Preliminary study on the efficacy of xerostomia treatment with sialocentesis targeting thyroid disease patients given radioiodine therapy

  • Kim, Euy-Hyun (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital) ;
  • Lee, Dong-Keon (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital) ;
  • Kim, Chang-Woo (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital) ;
  • Song, In-Seok (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital) ;
  • Jun, Sang-Ho (Department of Oral and Maxillofacial Surgery, Korea University Anam Hospital)
  • Received : 2019.07.05
  • Accepted : 2019.08.26
  • Published : 2019.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Radioiodine therapy has been widely used for thyroid disease patients, but hyposalivation and xerostomia may occur in 10~30% of patients. Sialocentesis is a procedure that removes inflammatory substances in the salivary duct and expands the duct for the secretion and delivery of saliva. In this study, thyroid disease patients treated with radioactive iodine were selected among the patients with xerostomia who visited the hospital, and the effect of sialocentesis was compared and analyzed. And then, comparison between the radioiodine therapy-experienced group and the non-radioiodine therapy-experienced group was conducted. Results: In this study, we studied xerostomia patients who underwent radioiodine therapy due to thyroid diseases and who underwent sialocentesis at the Korea University Anam Hospital. Sialocentesis is conducted by one surgeon. The study also compares the clinical symptoms before and after the surgery. After the procedure, the discomfort due to xerostomia was reduced, and the symptom was improved effectively. Conclusions: The results of this study showed that sialocentesis has a clinical effect in the treatment of xerostomia, which is a side effect of radioiodine therapy. In addition, the possibility of further clinical application of sialocentesis in the future is found.

Keywords

References

  1. Mandel SJ, Mandel L (2003) Radioactive iodine and the salivary glands. Thyroid 13(3):265-271 https://doi.org/10.1089/105072503321582060
  2. Rigler R, Scanlon P (1955) Radiation parotitis from radioactive iodine therapy. In: Proceedings of the staff meetings. Mayo Clinic
  3. Solans R, Bosch J-A, Galofre P, Porta F, Rosello J, Selva-O'Callagan A et al (2001) Salivary and lacrimal gland dysfunction (sicca syndrome) after radioiodine therapy. J Nuclear Med 42(5):738-743
  4. De Luca R, Vicidomini A, Trodella M, Tartaro G, Colella G (2014) Sialoendoscopy: a viable treatment for I131 induced sialoadenitis. Br J Oral Maxillofac Surg 52(7):641-646 https://doi.org/10.1016/j.bjoms.2014.01.025
  5. Bomeli SR, Schaitkin B, Carrau RL, Walvekar RR (2009) Interventional sialendoscopy for treatment of radioiodine-induced sialadenitis. Laryngoscope 119(5):864-867 https://doi.org/10.1002/lary.20140
  6. Wu C-B, Xi H, Zhou Q, Zhang L-M (2015) Sialendoscopy-assisted treatment for radioiodine-induced sialadenitis. J Oral Maxillofac Surg 73(3):475-481 https://doi.org/10.1016/j.joms.2014.09.025
  7. Kim JW, Han GS, Lee SH, Lee DY, Kim YM (2007) Sialoendoscopic treatment for radioiodine induced sialadenitis. Laryngoscope 117(1):133-136 https://doi.org/10.1097/01.mlg.0000247776.72484.62
  8. Lee D-K, Kim E-H, Kim C-W, Kang M-H, Song I-S, Jun S-H (2019) Sialolithotomy of the submandibular duct using sialendoscopy. Maxillofac Plast Reconstr Surg 41(1):24 https://doi.org/10.1186/s40902-019-0207-3
  9. Grove AS Jr, Di Chiro G (1968) Salivary gland scanning with technetium 99m pertechnetate. Am J Roentgenol 102(1):109-116 https://doi.org/10.2214/ajr.102.1.109
  10. Karagozoglu KH, Vissink A, Forouzanfar T, Brand HS, Maarse F, Jager DHJ (2018) Sialendoscopy enhances salivary gland function in Sjogren's syndrome: a 6-month follow-up, randomised and controlled, single blind study. Ann Rheumatic Dis 77(7):1025-1031 https://doi.org/10.1136/annrheumdis-2017-212672