대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제40권5호
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  • Pages.158-164
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  • 2019
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  • 1229-0807(pISSN)
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  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
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형상학적 변수에 따른 다공성 구조의 가변탄성계수를 기반으로 한 추간체유합보형재의 임상적 안전성 평가

Clinical Safety Evaluation of Interbody Fusion Cage Based on Tunable Elastic Modulus of the Cellular Structure According to the Geometrical Variables

  • 김성진 (건양대학교 의료신소재학과) ;
  • 이용경 (세종대학교 기계공학) ;
  • 최재혁 (세종대학교 기계공학) ;
  • 홍영기 (건양대학교 의료신소재학과) ;
  • 김정성 ((주)코렌텍 중앙기술연구소)
  • Kim, SeongJin (Department of Biomedical Materials, Konyang University) ;
  • Lee, YongKyung (Department of Mechanical Engineering, Sejong University) ;
  • Choi, Jaehyuck (Department of Mechanical Engineering, Sejong University) ;
  • Hong, YoungKi (Department of Biomedical Materials, Konyang University) ;
  • Kim, JungSung (Central R&D center, CORENTEC CO., LTD)
  • 투고 : 2019.09.19
  • 심사 : 2019.10.10
  • 발행 : 2019.10.31
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초록

The interbody fusion cage used to replace the degenerative intervertebral disc is largely composed of titanium-based biomaterials and biopolymer materials such as PEEK. Titanium is characterized by osseointergration and biocompatibility, but it is posed that the phenomenon such as subsidence can occur due to high elastic modulus versus bone. On the other hand, PEEK can control the elastic modulus in a similar to bone, but there is a problem that the osseointegration is limited. The purpose of this study was to implement titanium material's stiffness similar to that of bone by applying cellular structure, which is able to change the stiffness. For this purpose, the cellular structure A (BD, Body Diagonal Shape) and structure B (QP, Quadral Pod Shape) with porosity of 50%, 60%, 70% were proposed and the reinforcement structure was suggested for efficient strength reinforcement and the stiffness of each model was evaluated. As a result, the stiffness was reduced by 69~93% compared with Ti6Al4V ELI material, and the stiffness most similar to cortical bone is calculated with the deviation of about 12% in the BD model with 60% porosity. In this study, the interbody fusion cage made of Ti6Al4V ELI material with stiffness similar to cortical bone was implementing by applying cellular structure. Through this, it is considered that the limitation of the metal biomaterial by the high elastic modulus may be alleviated.

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