Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지
DOI QR코드

DOI QR Code

A Case report of MALT lymphoma in parotid gland

이하선에서 발견된 MALT 림프종 1례

  • Kim, Myeong Hee (Department of Otorhinolaryngology, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute) ;
  • Choi, Jong Joong (Department of Otorhinolaryngology, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute) ;
  • Ahn, Hong Geun (Department of Otorhinolaryngology, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute) ;
  • Park, Joong Su (Department of Otorhinolaryngology, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute) ;
  • Kim, Yeon Soo (Department of Otorhinolaryngology, College of Medicine, Konyang University Hospital, Konyang University Myunggok Medical Research Institute)
  • 김명희 (건양대학교병원 이비인후과학 교실) ;
  • 최종중 (건양대학교병원 이비인후과학 교실) ;
  • 안홍근 (건양대학교병원 이비인후과학 교실) ;
  • 박중수 (건양대학교병원 이비인후과학 교실) ;
  • 김연수 (건양대학교병원 이비인후과학 교실)
  • Received : 2018.12.10
  • Accepted : 2019.05.06
  • Published : 2019.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma has specific clinical and pathologic features. The most common site MALT lymphomas is the stomach; however, it can also occur in other organs, such as the salivary glands. MALT lymphoma is rare, but its prognosis is good. A 32-year-old man visited Konyang university hospital with parotid mass. Superficial partial parotidectomy was performed to exclude lymphoid neoplasms. IgH gene rearrangement analysis of the surgical specimen led to the diagnosis of MALT lymphoma. The patient underwent esophagogastroduodenoscopy, positron emission tomography-computed tomography, and whole-body bone scan. Regional or distant metastasis was not observed on staging workup. The patient underwent postoperative radiation therapy, there has been no recurrence of MALT lymphoma to date. Here, we report this rare case of parotid MALT lymphoma that was treated with surgery and postoperative radiation therapy.

Keywords

References

  1. Anacak Y, Kamer S. Primary MALT lymphoma of the salivary glands. In: Belkacemi Y, Mirimanoff R-O, Ozsahin M, editors. Management of Rare Adult Tumours. Paris: Springer Paris; 2010. p.123-126.
  2. Shin HA, Kahng H, Hwang E, Kim CH. A Case of Multifocal MALT Lymphoma in Salivary Glands. Korean J Otorhinolaryngol-Head Neck Surg. 2008;51:1166-1169.
  3. Zhu L, Wang P, Yang J, Yu Q. Non-Hodgkin lymphoma involving the parotid gland: CT and MR imaging findings. Dentomaxillofac Radiol. 2013;42:20130046. https://doi.org/10.1259/dmfr.20130046
  4. Vazquez A, Khan MN, Sanghvi S, Patel NR, Caputo JL, Baredes S, et al. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue of the salivary glands: a population-based study from 1994 to 2009. Head Neck. 2015;37:18-22. https://doi.org/10.1002/hed.23543
  5. Aydin S, Demir MG, Barisik NO. Extranodal Marginal Zone Lymphoma of the Parotid Gland. J Maxillofac Oral Surg. 2016;15:346-350. https://doi.org/10.1007/s12663-016-0882-x
  6. Ando M, Matsuzaki M, Murofushi T. Mucosa-associated lymphoid tissue lymphoma presented as diffuse swelling of the parotid gland. Am J Otolaryngol. 2005;26:285-288. https://doi.org/10.1016/j.amjoto.2005.01.011
  7. Zbaren P, Triantafyllou A, Devaney KO, Poorten VV, Hellquist H, Rinaldo A, et al. Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy? Eur Arch Otorhinolaryngol. 2018;275:2609-2613. https://doi.org/10.1007/s00405-018-5131-0
  8. Bahn YE, Lee SK, Kwon SY, Kim SP. Sonographic appearances of mucosa-associated lymphoid tissue lymphoma of the submandibular gland confirmed with sonographically guided core needle biopsy. J Clin Ultrasound. 2011;39:228-232. https://doi.org/10.1002/jcu.20754
  9. Zhang Y, Yu D, Huang K, Huang C, Liu H, Sun X, et al. Evaluation of the diagnostic value of immunoglobulin clonal gene rearrangements in patients with parotid gland MALT lymphoma using BIOMED-2 protocol. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;126:165-173. https://doi.org/10.1016/j.oooo.2018.03.005
  10. Bacon CM, Du MQ, Dogan A. Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists. J Clin Pathol. 2007;60:361-372. https://doi.org/10.1136/jcp.2005.031146
  11. Diss TC, Wotherspoon AC, Speight P, Pan L, Isaacson PG. B-cell monoclonality, Epstein Barr virus, and t(14;18) in myoepithelial sialadenitis and low-grade B-cell MALT lymphoma of the parotid gland. Am J Surg Pathol. 1995;19:531-536. https://doi.org/10.1097/00000478-199505000-00004
  12. Anacak Y, Miller RC, Constantinou N, Mamusa AM, Epelbaum R, Li Y, et al. Primary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys. 2012;82:315-320. https://doi.org/10.1016/j.ijrobp.2010.09.046