DOI QR코드

DOI QR Code

A Case of Infantile Fungal Urinary Tract Infection

  • Cho, Wonhee (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Jo, Young Min (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Oh, Yun Kyo (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Rim, Ji Woo (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Lee, Won Uk (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Choi, Kyongeun (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Ko, Jeong Hee (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Jeon, Yeon Jin (Department of Pediatrics, Gwangmyeong Sungae Hospital) ;
  • Choi, Yumi (Department of Pediatrics, Gwangmyeong Sungae Hospital)
  • Received : 2019.08.08
  • Accepted : 2019.10.15
  • Published : 2019.10.31

Abstract

Urinary tract infection is common in the pediatric population. The most common causative agents are bacteria, among which Escherichia coli is the most frequent uropathogen. Although fungal urinary tract infection is rare in the healthy pediatric population, it is relatively common among hospitalized patients. Fungus may be isolated from the urine of immunocompromised patients or that of patients with indwelling catheters. The most common cause of funguria is Candida albicans. Although more than 50% of Candida isolates belong to non-albicans Candida, the prevalence of non-albicans candiduria is increasing. Herein, we report a case of community-acquired candiduria in a 4-month-old immunocompetent male infant who had bilateral vesicoureteral reflux and was administered antibiotic prophylaxis. He was diagnosed with urinary tract infection caused by Candida lusitaniae and was managed with fluconazole.

Keywords

References

  1. Chang SL, Shortliffe LD. Pediatric urinary tract infections. Pediatr Clin North Am 2006;53:379-400. https://doi.org/10.1016/j.pcl.2006.02.011
  2. Guze LB, Haley LD. Fungus infections of the urinary tract. Yale J Biol Med 1958;30:292-305.
  3. Shaikh N, Morone NE, Bost JE, Farrell MH. Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J 2008;27:302-8. https://doi.org/10.1097/INF.0b013e31815e4122
  4. Behzadi P, Behzadi E, Yazdanbod H, Aghapour R, Akbari Cheshmeh M, Salehian Omran D. A survey on urinary tract infections associated with the three most common uropathogenic bacteria. Maedica (Buchar) 2010;5:111-5.
  5. Alanazi MQ, Alqahtani FY, Aleanizy FS. An evaluation of E. coli in urinary tract infection in emergency department at KAMC in Riyadh, Saudi Arabia: retrospective study. Ann Clin Microbiol Antimicrob 2018;17:3. https://doi.org/10.1186/s12941-018-0255-z
  6. Sobel JD, Fisher JF, Kauffman CA, Newman CA. Candida urinary tract infections--epidemiology. Clin Infect Dis 2011;52 Suppl 6:S433-S6. https://doi.org/10.1093/cid/cir109
  7. Thomas L, Tracy CR. Treatment of fungal urinary tract infection. Urol Clin North Am 2015;42:473-83. https://doi.org/10.1016/j.ucl.2015.05.010
  8. Kauffman CA, Vazquez JA, Sobel JD, Gallis HA, McKinsey DS, Karchmer AW, et al. Prospective multicenter surveillance study of funguria in hospitalized patients. The National Institute for Allergy and Infectious Diseases (NIAID) Mycoses Study Group. Clin Infect Dis 2000;30:14-8. https://doi.org/10.1086/313583
  9. Fisher JF, Sobel JD, Kauffman CA, Newman CA. Candida urinary tract infections--treatment. Clin Infect Dis 2011;52 Suppl 6:S457-S66. https://doi.org/10.1093/cid/cir112
  10. Gholamipour P, Mahmoudi S, Pourakbari B, Ashtiani MTH, Sabouni F, Teymuri M, et al. Candiduria in children: a first report from an Iranian referral pediatric hospital. J Prev Med Hyg 2014;55:54-7.
  11. Phillips JR, Karlowicz MG. Prevalence of Candida species in hospital- acquired urinary tract infections in a neonatal intensive care unit. Pediatr Infect Dis J 1997;16:190-4. https://doi.org/10.1097/00006454-199702000-00005
  12. Wynn JL, Tan S, Gantz MG, Das A, Goldberg RN, Adams-Chapman I, et al. Outcomes following candiduria in extremely low birth weight infants. Clin Infect Dis 2012;54:331-9. https://doi.org/10.1093/cid/cir800
  13. Kliegman RM, Stanton BF, St Geme III JW, Schor NF. Nelson textbook of pediatrics, 20th ed. Vol 1. Philadelphia: Elsevier, 2016
  14. Buck ML. A monthly newsletter for health care professionals from the children's medical center at the University of Virginia. Pediatric Pharmacotherapy 1997;3:1-4.
  15. Autmizguine J, Tan S, Cohen-Wolkowiez M, Cotton CM, Wiederhold N, Goldberg RN, et al. Antifungal susceptibility and clinical outcome in neonatal candidiasis. Pediatr Infect Dis J 2018;37:923-9. https://doi.org/10.1097/INF.0000000000001913