Annals of Clinical Neurophysiology

  • 제21권2호
  • /
  • Pages.105-107
  • /
  • 2019
  • /
  • 2508-691X(pISSN)
  • /
  • 2508-6960(eISSN)
대한임상신경생리학회 (The Korean Society of Clinical Neurophysiology)
권호 표지
DOI QR코드

DOI QR Code

Acute unilateral isolated abducens nerve palsy associated with anti-GM1 immunoglobulin M antibody

  • Son, Hyoshin (Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine) ;
  • Kim, Ahwon (Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine) ;
  • Hong, Sang Bin (Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine) ;
  • Koo, Dae Lim (Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine)
  • 투고 : 2019.02.08
  • 심사 : 2019.06.05
  • 발행 : 2019.07.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Acute ophthalmoparesis that includes the oculomotor, trochlear, or abducens nerve may occur as an initial presentation of Miller Fisher syndrome (MFS). The symptoms of MFS or variant forms of Guillain-Barre syndrome are pathogenically related to anti-GQ1b antibodies. We report a case of a 36-year-old man with unilateral isolated abducens nerve palsy associated with anti-GM1 antibody. To the best of our knowledge, this is the first report of unilateral isolated abducens nerve palsy with positivity for anti-GM1 immunoglobulin M antibody.

키워드

참고문헌

  1. Chou KL, Galetta SL, Liu GT, Volpe NJ, Bennett JL, Asbury AK, et al. Acute ocular motor mononeuropathies: prospective study of the roles of neuroimaging and clinical assessment. J Neurol Sci 2004;219:35-39. https://doi.org/10.1016/j.jns.2003.12.003
  2. Odaka M, Yuki N, Hirata K. Anti-GQ1b IgG antibody syndrome: clinical and immunological range. J Neurol Neurosurg Psychiatry 2001;70:50-55. https://doi.org/10.1136/jnnp.70.1.50
  3. Kaida K, Ariga T, Yu RK. Antiganglioside antibodies and their pathophysiological effects on Guillain-Barre syndrome and related disorders--a review. Glycobiology 2009;19:676-692. https://doi.org/10.1093/glycob/cwp027
  4. Willison HJ, Yuki N. Peripheral neuropathies and anti-glycolipid antibodies. Brain 2002;125(Pt 12):2591-2625. https://doi.org/10.1093/brain/awf272
  5. Lavallee P, Vidailhet M, Dussaule JC, Derkinderen P. Post-infectious ophtalmoparesis associated with anti-GM1 but not with anti-GQ1b antibodies. Eur J Neurol 2001;8:475-476. https://doi.org/10.1046/j.1468-1331.2001.00271.x
  6. Go T. Partial oculomotor nerve palsy associated with elevated anti-galactocerebroside and anti-GM1 antibodies. J Pediatr 2000;137:425-426. https://doi.org/10.1067/mpd.2000.107797
  7. Han TH, Kim DY, Park DW, Moon JH. Transient isolated lower bulbar palsy with elevated serum anti-GM1 and anti-GD1b antibodies during aripiprazole treatment. Pediatr Neurol 2017;66:96-99. https://doi.org/10.1016/j.pediatrneurol.2016.07.011
  8. Fusco C, Bertani G, Scarano A, Giustina ED. Acute ophthalmoparesis associated with anti-GM1, anti-GD1a, and anti-GD1b antibodies after enterovirus infection in a 6-year-old girl. J Child Neurol 2007;22:432-434. https://doi.org/10.1177/0883073807301921
  9. Katchanov J, Lunemann JD, Masuhr F, Meisel A, Moller H, Zschenderlein R. Isolated abducens nerve paresis associated with high titer of anti-asialo-GM1 following Campylobacter jejuni enteritis. J Neurol 2004;251:1404-1405. https://doi.org/10.1007/s00415-004-0538-5
  10. Caudie C, Quittard PA, Bouhour F, Vial C, Garnier L, Fabien N. Comparison of commercial tests for detecting multiple anti-ganglioside autoantibodies in patients with well-characterized immune-mediated peripheral neuropathies. Clin Lab 2013;59:1277-1287.