Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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A perspective on partially hydrolyzed protein infant formula in nonexclusively breastfed infants

  • Vandenplas, Yvan (KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel) ;
  • Munasir, Zakiudin (Department of Child Health, Faculty of Medicine, Universitas Indonesia) ;
  • Hegar, Badriul (Department of Child Health, Faculty of Medicine, Universitas Indonesia) ;
  • Kumarawati, Dewi (Department of Child Health, Udayana University Medical School/Sanglah Hospital) ;
  • Suryawan, Ahmad (Department of Child Health, Medical School, Unviersity of Airlangga) ;
  • Kadim, Muzal (Department of Child Health, Faculty of Medicine, Universitas Indonesia) ;
  • Djais, Julistio Tb (Department of Child Health, Medical School, University of Padjadjaran) ;
  • Basrowi, Ray Wagiu (Nestle Nutrition Institute) ;
  • Krisnamurti, Deni (Nestle Nutrition Institute)
  • 투고 : 2018.11.15
  • 심사 : 2019.01.12
  • 발행 : 2019.05.15
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초록

The World Health Organization recommends that infants should be exclusively breastfed for the first 6 months of life to provide optimal nutrition in this critical period of life. After this, infants should receive nutritionally adequate and safe complementary foods while breastfeeding continues for up to 2 years of age or beyond. For nonbreastfed infants, infant formula is an available option to provide the nutrition needed. Infant formula is usually prepared from industrially modified cow's milk and processed to adjust for the nutritional needs of infants. However, cow's milk is one of the most common causes of food allergy, affecting 2%-5% of all formula-fed infants during their first year of life. One strategy to prevent cow's milk allergy in nonbreastfed infants is the use of partially hydrolyzed formula (pHF) in high-risk infants, which are infants born in families with atopic disease. However, based on an epidemiological study, approximately half of the infants who develop allergy are not part of the at-risk group. This is because the non-at-risk group is significantly larger than the at-risk group and the non-at-risk infants have approximately 15% risk of developing allergies. This study aimed to evaluate the effects of partially hydrolyzed whey formula (pHF-W) in nonbreastfed infants and determine whether pHF-W can prevent atopic disease in high-risk infants and can be used as routine starter formula regardless of the allergy risk status.

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참고문헌

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피인용 문헌

  1. Should partially hydrolyzed infant formula be given to the general infant population for the primary prevention of allergic disease? vol.62, pp.9, 2019, https://doi.org/10.3345/kjp.2019.00255
  2. The Role and Place of Partially Hydrolysed Protein Infant Formulas in the Nutrition of Full-term Children: Digestive Comfort and Allergy Prevention vol.19, pp.4, 2020, https://doi.org/10.15690/vsp.v19i4.2135
  3. The Effects of a Partially Hydrolyzed Formula with Low Lactose and Probiotics on Mild Gastrointestinal Disorders of Infants: A Single-Armed Clinical Trial vol.13, pp.10, 2019, https://doi.org/10.3390/nu13103371