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Comparison of the biodegradability in the membranes for the guided bone regeneration: preliminary study

  • Lee, Chang-Hyeon (Dept. of Oral and Maxillofacial Surgery, Sacred Heart Hospital, Hallym University) ;
  • Kang, Yei-Jin (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University) ;
  • Jo, You-Young (Sericultural and Apicultural Division, National Institute of Agricultural Science, RDA) ;
  • Kweon, HaeYong (Sericultural and Apicultural Division, National Institute of Agricultural Science, RDA) ;
  • Kim, Seong-Gon (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
  • Received : 2019.07.11
  • Accepted : 2019.08.27
  • Published : 2019.09.28

Abstract

In this study, 4 different types of GBR membrane were undergone for bio-degradability test; Silk mat from silkworm cocoon (TDI), silk mat from flatwise-spun (FS), collagen membrane (OssGuide), and dPTFE membrane (Cytoplast). Each material was segmented in 10.00 mm length and 0.3 mm thickness. The samples were put into the normal saline at $37^{\circ}C$ for 2 weeks. After that, yield strength and tensile strain were measured and compared them with those of before treatment. The morphology of the membranes was observed by SEM. Tensile strain of FS was significantly increased at 2 weeks' normal saline treatment (P=0.018). When compared to OssGuide, TDI and FS showed significantly higher tensile strain at 2 weeks' normal saline treatment (P<0.05). In the SEM images, there were no significant changes in Cytoplast, TDI, and FS after 2 weeks' treatment. However, OssGuide showed damaged surface after 2 weeks' treatment. In conclusion, both TDI and FS did not have any evidence of biodegradability at 2 weeks' observation in normal saline treatment. However, OssGuide showed more than 20 % decrease in yield strength and tensile strain.

Keywords

References

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