Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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CT and MRI Features of Solitary Fibrous Tumor of the Liver: A Case Report

간에 발생한 고립성 섬유종: CT와 MRI 소견을 포함한 증례 보고

  • Nah, Yoo Kyeong (Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School) ;
  • Shin, Sang Soo (Department of Radiology, Chonnam National University Hospital, Chonnam National University Medical School) ;
  • Heo, Suk Hee (Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School) ;
  • Jeong, Yong Yeon (Department of Radiology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School)
  • 나유경 (전남대학교 의과대학 화순전남대학교병원 영상의학과) ;
  • 신상수 (전남대학교 의과대학 전남대학교병원 영상의학과) ;
  • 허숙희 (전남대학교 의과대학 화순전남대학교병원 영상의학과) ;
  • 정용연 (전남대학교 의과대학 화순전남대학교병원 영상의학과)
  • Received : 2019.01.03
  • Accepted : 2019.02.21
  • Published : 2019.11.01
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Abstract

Solitary fibrous tumors (SFTs) are a unique group of soft tissue tumors originating from fibroblastic or myofibroblastic tissue. SFTs rarely occur in the liver, with less than 30 cases reported in the literature. We report a case of SFT of the liver presenting unique imaging features on CT and MRI. A 52-year-old woman presented with an incidentally detected hepatic mass that showed homogeneous strong enhancement, starting from the arterial phase until the delayed phase images on CT. On the T2-weighted MR image, the mass was heterogeneously hyperintense with multifocal hypointense dots and bands within the mass. The mass was microscopically characterized by bland-looking, ovoid to spindle shaped cells with stromal and perivascular hyalinization. Immunohistochemical studies showed reactivity for CD34.

고립성 섬유종은 섬유모세포 혹은 근섬유모세포 조직으로부터 기원한 연조직 종양이다. 고립성 섬유종이 간에 발생하는 경우는 흔하지 않으며, 30예 이하의 증례가 보고된 바 있다. 본 연구에서는 컴퓨터단층촬영과 자기공명영상에서 독특한 소견을 보이는 간의 고립성 섬유종 증례를 보고하고자 한다. 52세 여자 환자가 우연히 발견된 간 종괴를 주소로 내원하였다. 종양은 컴퓨터단층촬영에서 동맥기부터 지연기까지 균질하고 강한 조영증강을 보였고, 자기공명영상에서는 T2 강조 영상에서 불균질한 높은 신호 강도를 보이며 내부 여러 군데에 신호 강도가 낮은 점과 띠를 포함하고 있었다. 병리조직학적 검사에서 종양세포들은 타원형 혹은 방추형이었으며, 세포질 및 혈관주위 유리질화가 관찰되었다. 또한 면역조직화학 검사에서 CD34에 양성을 보였다.

Keywords

Acknowledgement

This work was supported by the funds from the National Research Foundation of Korea (2018R1D1A3B07043473) and the Chonnam National University Hospital Research Institute of Clinical Medicine in South Korea (CRI18091-2).

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