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Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
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Scientific exploration on physiological basis of Svedana Karma (Sudation): A clinical application of heat stress.

  • Yadav, Saurabh (Himalayiya Ayurvedic P.G. Medical College& Hospital) ;
  • Verma, Vandana (Department of KriyaSharir, Faculty of Ayurveda, Institute of Medical Science) ;
  • Abhinav, Abhinav (Department of KayaChikitsa, Faculty of Ayurveda, Institute of Medical Science)
  • Received : 2019.07.25
  • Accepted : 2019.08.13
  • Published : 2019.08.30
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Abstract

Now researchers have focused attention on exploring the mechanism of acute responses of heat stress given in heat therapy that ultimately promotes the long term health benefits. Heat therapy is not a new idea rather it was practiced since thousands years back in the form of hot bath, sauna bath, steam room. Similarly in Ayurveda there is very comprehensive description of heat therapy in the form of Svedan karma (Sudation therapy). Svedan is a process to induce sweating artificially in a patient who had already undergone Snehan. Svedan is applied for purification of body, as well as in management of various disorders originated due to vitiation of Vata, Kapha Dosha, Meda Dhatu and musculoskeletal disorders. It produces various beneficial effects by augmenting the Agni like clears the channels, liquefies the deposited Dosha, regulates Vata Dosha, helps in removal and pacification of Dosha, augments metabolism (Agni Deepan), increases appetite, flexibility in body parts, softness and shining of skin, removes coldness, stiffness, drowsiness, improves joint motility. However, Svedana karma is vastly used by Ayurveda Physicians in treatment of various disorders but the mechanisms of beneficial effects produced by Svedan Karma are yet not completely explored on scientific basis. In this article, we will discuss and try to establish a possible mechanism of action of Svedana karma in relation to heat stress, mitochondrial adaptation, heat shock protein (HSP) and glucocorticoids as these are secreted under stressful conditions.

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References

  1. Binder RJ. Functions of heat shock proteins in pathways of the innate and adaptive immune system. Journal of Immunology. 2014:193 (12): 5765-71. https://doi.org/10.4049/jimmunol.1401417
  2. Brunt VE, Howard MJ, Francisco MA, Ely BR, Minson CT. Passive heat therapy improves endothelial function, arterial stiffness and blood pressure in sedentary humans. J Physiol. 2016:(18):5329-42. https://doi.org/10.1113/JP272453
  3. Charles LR, Andrew HM. When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders. Am J Psychiatry.2003:16(9).
  4. Hafen PS, Preece CN, Sorensen JR, Hancock CR, Hyldahl RD. Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J ApplPhysiol (1985). 2018:125(5):1447-1455.
  5. Hooper PL. Inflammation, heat shock proteins, and type 2 diabetes. Cell Stress Chaperones. 2009:14(2):113-115. https://doi.org/10.1007/s12192-008-0073-x
  6. Iguchi M, Littmann AE, Chang SH, Wester LA, Knipper JS, Shields RK. Heatstress and cardiovascular, hormonal, and heat shock proteins in humans. J Athl Train. 2012:47(2):184-90 https://doi.org/10.4085/1062-6050-47.2.184
  7. Jain AK. Textbook of Physiology. Revised edition. (New Delhi, India: Avichal Publishing Company), pp. 739-40, 2009.
  8. Jesper GS, Torsten NK, Volker L. The evolutionary and ecological role of heat shock proteins. 2003:6:1025-1037. https://doi.org/10.1046/j.1461-0248.2003.00528.x
  9. Krishanamurthy KH. Bhela Samhita of Bhela. Sutrasthana; Svedaadhyaya: Chapter 22, verse 1.Varanasi :ChowkhambhaVishwabharti, pp.95, 2013.
  10. Murthy Shrikantha KR. Editor (reprint edition) Sushruta Samhita of Sushruta. Varanasi: ChoukhambhaOrientalia, 2004.
  11. Murthy Srikantha KR, editor (9thEdition).AshtangaHridyam of Vagbhata. Varanasi: ChowkhambaKrishndas Academy.
  12. Pandey G. HaritaSamhit of Harita. (1st edition) Fourth sthana, Svedavidhiadhyaya. Varanasi: Chowkhambhasanskrita Series, 2014.
  13. Riezman H. Why do cells require heat shock proteins to survive heat stress? Cell Cycle. 2004:3(1):60-62. https://doi.org/10.4161/cc.3.1.625
  14. Sharma RK, Das B. Charak Samhita of Agnivesh. Varanasi: ChoukhmbhaSanskrita Series office, 2008.
  15. Singh N, Chaudhary A. A comparative review study of SnehaKalpana (Paka) vis-a vis liposome. AYU. 2011;32:103-8 https://doi.org/10.4103/0974-8520.85740
  16. Thomas KN. Harnessing heat for health: A clinical application of heat stress. Temperature (Austin). 2017:4(3):208-210. https://doi.org/10.1080/23328940.2017.1317379
  17. Tiwari PV. Kashyapasamhita of Vriddhajeevakatantra. Varanasi: ChowkhambhaVishwabharti, 2013.
  18. Tripathi KD. Essentials of medial pharmacology (sixeth edition). Jaypee Brothers medical publishers (p) LTD, 2010.
  19. Vangelova K, Deyanov C, Velkova D, Ivanova M, Stanchev V. The effect of heat exposure on cortisol and catecholamine excretion rates in workers in glass manufacturing unit, Cent Eur J Public Health. 2002:10(4):149-52.
  20. Walter S, Buchner J. Molecular chaperones--cellular machines for protein folding. 2002:41 (7):1098-113. https://doi.org/10.1002/1521-3773(20020402)41:7<1098::AID-ANIE1098>3.0.CO;2-9