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인후부 이물감 호소에 따른 위식도역류질환 환자의 임상적 특징 비교

Comparison of the Clinical Characteristics of Patients with Gastroesophageal Reflux Disease According to Globus Sensation

  • 백소영 (경희대학교 대학원 임상한의학과) ;
  • 황미니 (경희대학교 대학원 임상한의학과) ;
  • 고휘형 (경희대학교 대학원 임상한의학과) ;
  • 김동윤 (경희대학교 대학원 임상한의학과) ;
  • 이하늘 (경희대학교 대학원 임상한의학과) ;
  • 정해인 (경희대학교 대학원 임상한의학과) ;
  • 하나연 (경희대학교 대학원 임상한의학과) ;
  • 김진성 (경희대학교 대학원 임상한의학과)
  • Baek, So-young (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Hwang, Mi-ni (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Ko, Whee-hyoung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Dong-yoon (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Lee, Ha-nul (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Jeong, Hae-in (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Ha, Na-yeon (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Jin-sung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
  • 투고 : 2019.03.25
  • 심사 : 2019.07.06
  • 발행 : 2019.06.30

초록

Objectives: This study aimed to investigate the clinical characteristics of patients with gastroesophageal reflux disease (GERD) according to globus sensation (GS). Methods: We reviewed the clinical records of 29 GERD patients who visited the Department of Digestive Diseases of Kyung Hee University Korean Medicine Hospital from March 1, 2018 to February 28, 2019. The subjects were classified according to the presence of globus sensation, and the two groups were compared in terms of heart rate variability (HRV) and the Ryodoraku results. Results: In comparing the GERD with GS group (GS group) and the GERD without GS group (non-GS group), a significant difference was found in the duration of symptom and several HRV parameters. The duration of the symptom in the GS group was significantly longer than that in the non-GS group. The non-GS group showed a significantly higher value of total power and high frequency than the GS group. Conclusions: The results suggest a significant difference in the stress level between patients with GERD with GS and those without GS. When approaching patients with GERD without GS, their stress status should be considered.

키워드

참고문헌

  1. Jung HK, Hong SJ, Jo YJ, Jeon SW, Cho YK, Lee KJ, et al. Updated Guidelines 2012 for Gastroesophageal Reflux Disease. Korean J Gastroenterol 2012;60(4):195-218. https://doi.org/10.4166/kjg.2012.60.4.195
  2. Han GJ, Leem JT, Lee NL, Kim JS, Park JW, Lee JH. Development of a Standard Tool for Pattern Identification of Gastroesophageal Reflux Disease (GERD). J Int Korean Med 2015;36(2):122-52. https://doi.org/10.13048/jkm.15039
  3. Jeon SG, Sohn CI, Kim JE, Park KH, Whang IS, Kim EJ, et al. Prevalence of gastroesophageal reflux in routine check-up subjects. Korean J Intern Med 2000;58(2):145-51.
  4. Lee SH, Choi MG, Park SH, Choi H, Moon SB, Choo KY, et al. The Clinical Spectrum of Gastroesophagel Reflux Disease in Korea. Korean J of Gastrointestinal 2000;6(1):1-10.
  5. Klauser AG, Schindlbeck NE, Muller-Lissner SA. Symptoms in gastro-oesophageal reflux disease. Lancet 1990;335(8683):205-8. https://doi.org/10.1016/0140-6736(90)90287-F
  6. Vakil N, Van Zanten SV, Kahrilas P, Dent J, Jones R. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol 2006;101(8):1900-20. https://doi.org/10.1111/j.1572-0241.2006.00630.x
  7. Lee KS, Kim NY, Park RY, Kim CH, Kim HY, Park YS, et al. Origial Articles : The role of endoscopy, 24 hour ambulatory esophageal pH monitor and bernstein test for gastrosophageal reflux disease and its relationship with symptom. Korean J Med 2006;70(2):145-56.
  8. Yi SY, Lee SK, Kim MH, Han DS, Kim JW, Min YI, et al. Epidemiologic Study of Reflux Esophagitis in General Health Screening People. Korean J of Med 1994;46(4):514-20.
  9. Kim HY, Kim N, Kim SM, Seo JH, Park YS, Hwang JH, et al. Clinical spectrum and risk factors of erosive and non-erosive GERD in health check-up subjects. Korean J of Med 2006; 71(5):491-500.
  10. Hwang EY, Chung SY, Kim JW, Suh JW, Suh HU. A Case Report of Conversion Disorder Patient with Globus Hystericus and Swallowing difficulty. J of Oriental Neuropsychiatry 2009; 20(2):197-206.
  11. Chon JS, Chun SI, Cho KJ, Jin MR, Kim TS, Kim DY, et al. Assessment of Autonomic Nervous Function in Young Adults by Power Spectral Analysis of Heart Rate Variability. J Korean Acad Rehabil Med 1997;21(5):923-35.
  12. Choi WS. Heart Rate Variadility and the Measurement of Stress. Korean J of Stress Research 2005;13(2):59-63.
  13. Yang DH, Park YB, Correlation between Pulserespiration Ratio and Heart Rate Variability. J of Korea Institue Oriental medical diagnostics 2006;10(2):104-20.
  14. McCraty R, Watkins A. Autonomicassessment report: A comprehensive heart rate variability analysis. Institute of Heart Math 1996:1-42.
  15. Lim DJ, Hwang GH, Hwang JS, Cho HS, Kim KH, Kim KS. Study of the Relation of Autonomic Nerve System and Peripheral Facial Palsy by the Heart RatMe Variability. The J Korean Acupuncture & Moxibustion Society 2005;22(6):51-60.
  16. Um EJ, Jeong SH, Park WR, Lee BJ, Na BJ. Study of Correlation between Insomnia and Autonomic Nervous System Functions by analysis of Heart Rate Variability. J Int Korean Med 2009;30(110):167-74.