The korean journal of orthodontics (대한치과교정학회지)

The Korean Association Of Orthodontists (대한치과교정학회)
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Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy

  • Park, Kyung-Jin (Department of Cariology, Endodontology and Periodontology, University of Leipzig) ;
  • Kroker, Tessa (Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Gottingen) ;
  • Gross, Uwe (Institute for Medical Microbiology, Center for Hygiene and Human Genetics, University Medical Center Gottingen) ;
  • Zimmermann, Ortrud (Institute for Medical Microbiology, Center for Hygiene and Human Genetics, University Medical Center Gottingen) ;
  • Krause, Felix (Department of Cariology, Endodontology and Periodontology, University of Leipzig) ;
  • Haak, Rainer (Department of Cariology, Endodontology and Periodontology, University of Leipzig) ;
  • Ziebolz, Dirk (Department of Cariology, Endodontology and Periodontology, University of Leipzig)
  • Received : 2018.11.29
  • Accepted : 2019.01.23
  • Published : 2019.07.25
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Abstract

Objective: To evaluate the effectiveness of three different caries-preventing agents on artificial caries in a Streptococcus mutans-based caries model. Methods: Sixty-five caries-free human molar enamel blocks were treated with a demineralization solution and a remineralization solution. The specimens were assigned to the following groups according to the caries-protective product applied: group A, chlorhexidine varnish; group B, fluoride-releasing chemically cured sealant; group C, fluoride-releasing lightcured sealant; group D, positive control (specimens that were subjected to de- and remineralization cycles without treatment with any caries-protective agents); and group E, negative control (specimens that were not subjected to de- and remineralization cycles). Samples in groups A-D were stored in demineralization solution with S. mutans and thereafter in artificial saliva. This procedure was performed for 30 days. Average fluorescence loss (${\Delta}F$) and surface size of the lesions were measured using quantitative light-induced fluorescence at baseline and on the 7th, 14th, and 30th days. Results: After 30 days, group A demonstrated a significant increase in ΔF and the surface size of the lesions, no significant difference in comparison with the positive control group, and a significant difference in comparison with the negative control group. Group B showed no significant changes in both parameters at any of the measurement points. While group C showed increased ${\Delta}F$ after 14 days, no significant fluorescence change was observed after 30 days. Conclusions: Both fluoride-releasing sealants (chemically or light-cured) show anti-cariogenic effects, but the use of chlorhexidine varnish for the purpose of caries protection needs to be reconsidered.

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References

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