Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
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The Gastroesophageal Reflux Disease Questionnaire in Adolescents: What Is the Best Cutoff Score?

  • Artanti, Dian (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Hegar, Badriul (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Kaswandani, Nastiti (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Soedjatmiko, Soedjatmiko (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Prayitno, Ari (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Devaera, Yoga (Department of Child Health, Faculty of Medicine, University of Indonesia) ;
  • Vandenplas, Yvan (KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel)
  • Received : 2018.09.18
  • Accepted : 2018.11.06
  • Published : 2019.07.15
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Abstract

Background: A self-assessment questionnaire, the GERD-Questionnaire (GERD-Q) was used to determine the prevalence of GERD in adolescents, describe the related factors, and determine the impact on quality of life (QoL). Methods: The incidence of GERD was evaluated using the GERD-Q in adolescents aged 12-18 years. The Pediatric Gastroesophageal Reflux Disease Symptom Questionnaire and Quality of Life Questionnaire (PGSQ-A) for adolescents were additionally administered. Some factors considered related to GERD were also evaluated. Results: The 520 adolescents were included. The prevalence of suspected GERD, according to a GERD-Q cutoff score of ${\geq}7$ was 32.9%, and those drinking soda were 1.7 times more likely to have GERD (95% confidence interval, 1.3-2.2; p<0.001). However, soda consumption was not a risk factor for development of GERD symptoms. Applying a cutoff score of ${\geq}8$, only 10.9% of the participants had a positive GERD score, but the association with soda consumption persisted. The median PGSQ-A score in subjects suspected of GERD was 8 (range 0-37) on weekends and 1 (range 0-17) during weekdays (p<0.001) compared to those not suspected of GERD, with a median of 2 (range 0-27) during weekends and 0 (range 0-10) during weekdays. Heartburn, regurgitation, and extraesophageal symptoms correlated significantly with QoL (p<0.001). Conclusion: The prevalence of suspected GERD in adolescents was 32.9% or 10.9%, depending on the cutoff score used. There was a statistically significant difference in PGSQ-A scores between the subjects suspected or not of GERD, indicating an impaired QoL.

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References

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