Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Enteric Pathogens in Pediatric Patients with Acute Gastroenteritis in Gyeongju, Korea: A Retrospective Study for 7 Years in a Regional Hospital

  • Cho, Seung-Man (Department of Pediatrics, College of Medicine, Dongguk University) ;
  • Lee, Dong Seok (Department of Pediatrics, College of Medicine, Dongguk University) ;
  • Ha, Gyoung Yim (Department of Laboratory Medicine, Dongguk University School of Medicine, Dongguk University) ;
  • Son, Dong-Chul (GyeongSangBukdo Government Public Institute of Health & Environment) ;
  • Lee, Chang Il (GyeongSangBukdo Government Public Institute of Health & Environment)
  • Received : 2018.10.04
  • Accepted : 2018.12.18
  • Published : 2019.06.28
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Abstract

Acute diarrhea is a global health problem that causes high morbidity and mortality in children. Notably, enteric pathogen co-infections have been suggested to play an important role in gastroenteritis. In this study, we analyzed 1150 stool specimens of patients who visited the pediatric ward of Dongguk University Hospital in Gyeongju province from January 2011 to December 2017. The average isolation rate of potential stool pathogens over 7 years was 37.3% (429/1150), and coinfections were observed in 51 patients (51/429; 11.9%). In the 51 co-infection cases, the most frequent type of co-infection was found to be that of virus-bacteria (33/51). The most frequently detected bacterial pathogen among the co-infected cases was Clostridium spp. (22/51), out of which Clostridium perfringens was found to be the main pathogen (16/22; 72.7%). Escherichia coli spp. were the second most common bacterial pathogens found in 12 cases (12/51; 23.5%), with 10 cases of E. coli EPEC. Furthermore, the most frequently implicated viral pathogen among the co-infected cases was norovirus (16/51), followed by rotavirus (12/51).

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References

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