한국미생물·생명공학회지 (Microbiology and Biotechnology Letters)

  • 제47권2호
  • /
  • Pages.201-210
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  • 2019
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  • 1598-642X(pISSN)
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  • 2234-7305(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
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Biotransformation of Ginsenosides by Eoyukjang-derived Lactic Acid Bacteria in Mountain-cultivated Ginseng

  • Lee, Hyojin (Department of Systems Biotechnology, Chung-Ang University) ;
  • Ahn, Seung Il (Department of Systems Biotechnology, Chung-Ang University) ;
  • Yang, Byung Wook (School of Industrial Bio-Pharmaceutical Science (LINC+ Project), Semyung University) ;
  • Park, Jong Dae (Central Research Institute, Korean Ginseng Research Co., Ltd.) ;
  • Shin, Wang Soo (Central Research Institute, Korean Ginseng Research Co., Ltd.) ;
  • Ko, Sung Kwon (The Department of Oriental Medical Food and Nutrition, Semyung University) ;
  • Hahm, Young Tae (Department of Systems Biotechnology, Chung-Ang University)
  • 투고 : 2018.10.02
  • 심사 : 2018.12.03
  • 발행 : 2019.06.28
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초록

Biotransformation of ginsenosides by microorganisms alters the absorption and bioavailability of ginseng as a medicinal herb. In this study, we isolated two kinds of fermenting microorganisms from Eoyukjang, which is a traditional Korean fermented food made from soybean. Next, we identified and detected their ability to convert major ginsenosides to compound K. The two microorganisms, referred to as R2-6 and R2-15, had 100% similarity with Lactobacillus plantarum subsp. plantarum ATCC $14917^T$ and Lactobacillus rhamnosus JCM $1136^T$, respectively. The optimal pH and growth temperature of the isolates were determined to be pH 6-7 and $30^{\circ}C$. After fermentation for 30 days, the major ginsenosides in the mountain-cultivated ginseng were transformed to the highly bioactive ginsenoside, compound K, in the final product.

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참고문헌

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