Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Risk Factors of Delirium in ICU Patients with Acute Poisoning

중환자실 급성중독환자에서 섬망의 위험인자

  • Kim, Hee Yeon (Department of Emergency Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Cha, Kyung Man (Department of Emergency Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) ;
  • So, Byung Hak (Department of Emergency Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea)
  • 김희연 (가톨릭대학교 성빈센트병원 응급의학과) ;
  • 차경만 (가톨릭대학교 성빈센트병원 응급의학과) ;
  • 소병학 (가톨릭대학교 성빈센트병원 응급의학과)
  • Received : 2019.04.16
  • Accepted : 2019.05.29
  • Published : 2019.06.30
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Abstract

Purpose: This study estimated the incidence of delirium and associated risk factors and outcomes in ICU patients with acute poisoning. Methods: Data were collected from ICU patients over 18 years of age that were admitted via the emergency center after presenting with poisoning from 2010 to 2015. Delirium was assessed retrospectively using the Intensive Care Delirium Screening Checklist (ICDSC). Risk factors were evaluated by univariate and multivariate analysis. Results: A total of 199 patients participated in this study and 68 (34.2%) were diagnosed with delirium based on the ICDSC score. The delirium group showed a significantly higher association with prolonged length of stay in the hospital and ICU in comparison with the non-delirium group. The delirium group was associated with greater use of physical restraint. A statistically greater number of patients with pharmaceutical substance poisoning developed delirium over a short period of time than those with non-pharmaceutical substance poisoning. There was no significant difference between the two groups with respect to age, sex, past history, GCS score, vital signs, application of ventilator care and renal replacement therapy. Conclusion: The finding that the delirium group had a greater length of stay in both the hospital and the ICU is consistent with the results of previous worldwide studies of the effects of delirium on the prognosis of patients who were admitted to the ICU, suggesting the possibility for domestic application. Additionally, use of physical restraint was positively related to the incidence of delirium. Thus, interventions for minimizing the use of physical restraints and considering alternatives are needed.

Keywords

References

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