Journal of Food Hygiene and Safety (한국식품위생안전성학회지)

The Korean Society of Food Hygiene and Safety (한국식품위생안전성학회)
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Monitoring of Methanol Levels in Commercial Detergents and Rinse Aids

시판 세척제 및 헹굼보조제 중 메탄올 함량 모니터링

  • Park, Na-youn (Department of Health Environment Safety, Eulji University) ;
  • Yang, Heedeuk (Food Technology & Service, Eulji University) ;
  • Lee, Jeoungsun (Department of Health Environment Safety, Eulji University) ;
  • Kim, Junghoan (Food Technology & Service, Eulji University) ;
  • Park, Se-Jong (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Choi, Jae Chun (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Kim, MeeKyung (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Kho, Younglim (Department of Health Environment Safety, Eulji University)
  • 박나연 (을지대학교 보건환경안전학과) ;
  • 양희득 (을지대학교 식품산업외식학과) ;
  • 이정선 (을지대학교 보건환경안전학과) ;
  • 김정환 (을지대학교 식품산업외식학과) ;
  • 박세종 (식품의약품안전평가원 첨가물포장과) ;
  • 최재천 (식품의약품안전평가원 첨가물포장과) ;
  • 김미경 (식품의약품안전평가원 첨가물포장과) ;
  • 고영림 (을지대학교 보건환경안전학과)
  • Received : 2019.04.17
  • Accepted : 2019.06.01
  • Published : 2019.06.30
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Abstract

Methanol is a toxic alcohol used in various products such as antifreeze, detergent, disinfectant and industrial solvent. In the human body, methanol is oxidized to formaldehyde and formic acid, which can lead to metabolic acidosis, optic nerve impairment, and death. In this study, the methanol levels in detergents (n=191) and rinse aids (n=13) were analyzed by gas chromatography-headspace-mass spectrometry (GC-HS-MS). Limit of detection was 1.09 mg/kg, accuracy and precision were 91.1-97.9% and <10%, and it was suitable for quantitative analysis. This analysis method was simple and fast with a higher recovery rate than the conventional MFDS (Ministry of Food and Drug Safety) method of diluting the sample in water and putting it in a headspace vial.

메탄올은 부동액, 세제, 살균제, 소독제 및 공업용매 등 다양한 분야에서 사용되는 독성 알코올이며, 섭취, 경피흡수 및 흡입을 통해 인체에 노출된다. 체내에서 메탄올은 포름알데히드와 포름산으로 산화되며, 이러한 생성물을 대사산증, 시신경장애를 일으키고, 심한 경우 사망에 이르기도 한다. 본 연구에서는 국내에서 유통되는 세척제 및 헹굼보조제 중 메탄올의 함량을 모니터링하고자 하였으며, 기존의 식약처에서 고시한 방법보다 더 간단하고 빠른 GC-HS-MS방법으로 진행하였다. 본 분석법은SIM 모드로 진행하였고(메탄올 31 m/z 및 이소프로판올 45 m/z), LOD는 1.09 mg/kg으로 계산되었으며, 정확도와 정밀도는 각각 91.1-97.9%와 10%이하로 나타나 정량분석에 적합한 수준임을 확인하였다. 본 연구는 세척제 중 메탄올 함량을 모니터링한 최초의 연구로써 가치가 있다고 판단된다.

Keywords

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