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Application of Dual-Frequency Ultrasound for Treating the Ulcerative Necrobiosis Lipoidica

  • Hong, Seok Won (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Park, Eun Soo (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Kim, Seok Hwan (Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine) ;
  • Jung, Min Jung (Department of Pathology, Soonchunhyang University, College of Medicine)
  • Received : 2019.11.26
  • Accepted : 2019.12.08
  • Published : 2019.12.31

Abstract

Necrobiosis lipoidica (NL) is a rare, idiopathic, chronic granulomatous inflammatory disease of collagen degeneration with the risk of ulceration. Many procedures have been proposed to treat this rare disease. In this study, we applied LDM®-MED for the management of NL, and this condition in our patient was chronic and refractory to other therapeutic options. To the best of our knowledge, no study has explored treatment of NL using ultrasound. Our results suggest that application of LDM®-MED seems to be an effective treatment option for NL. Long-term and systematic studies are needed to determine whether such application of LDM®-MED will be an innovative and effective treatment option for NL and various kinds of chronic wounds.

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Acknowledgement

This work was supported by the Soonchunhyang University Research Fund.