Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제45권2호
  • /
  • Pages.76-82
  • /
  • 2019
  • /
  • 2234-7550(pISSN)
  • /
  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
권호 표지
DOI QR코드

DOI QR Code

Is treatment with platelet-rich fibrin better than zinc oxide eugenol in cases of established dry socket for controlling pain, reducing inflammation, and improving wound healing?

  • Paul, Sam (Department of Orthodontics and Dentofacial Orthopaedics, Educare Institute of Dental Sciences) ;
  • Choudhury, Rupshikha (Department of Oral and Maxillofacial Surgery, Regional Dental College) ;
  • Kumari, Nandini (Faculty of Dental Sciences, Trauma Centre, Banaras Hindu University) ;
  • Rastogi, Sanjay (Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Centre (KDCRC)) ;
  • Sharma, Ashish (Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Centre (KDCRC)) ;
  • Singh, Vikas (Department of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre (TMDCRC)) ;
  • Laskar, Shyamalendu (Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Centre (KDCRC)) ;
  • Dubey, Tushar (Department of Oral and Maxillofacial Surgery, Kothiwal Dental College and Research Centre (KDCRC))
  • 투고 : 2018.02.20
  • 심사 : 2018.04.21
  • 발행 : 2019.04.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives: To appraise the effectiveness of platelet-rich fibrin (PRF) in the management of established dry socket in terms of pain, inflammation, and wound healing. Materials and Methods: Two hundred patients with established alveolar osteitis were studied to determine the efficacy of PRF and zinc oxide eugenol (ZOE) for pain control, inflammation reduction, and wound healing. Patients were randomly allocated to Group A (PRF) or Group B (ZOE). Patients were examined on the 1st, 3rd, 7th, and 14th postoperative day and evaluated for pain using visual analogue scale scores, inflammation with a gingival index score, and wound healing through a determination of the number of bony walls exposed. Results: Group A showed better results in terms of pain remission, control of inflammation, and wound healing compared to Group B. Results between groups were statistically significant (P<0.05). Conclusion: PRF is a better alternative than ZOE for the effective management of alveolar osteitis.

키워드

참고문헌

  1. Bowe DC, Rogers S, Stassen LF. The management of dry socket/alveolar osteitis. J Ir Dent Assoc 2011;57:305-10.
  2. Crawford JY. Dry socket. Dent Cosms 1896;38:929-31.
  3. Metin M, Tek M, Sener I. Comparison of two chlorhexidine rinse protocols on the incidence of alveolar osteitis following the surgical removal of impacted third molars. J Contemp Dent Pract 2006;7:79-86.
  4. Bloomer CR. Alveolar osteitis prevention by immediate placement of medicated packing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90:282-4. https://doi.org/10.1067/moe.2000.108919
  5. Blum IR. Contemporary views on dry socket (alveolar osteitis): a clinical appraisal of standardization, aetiopathogenesis and management: a critical review. Int J Oral Maxillofac Surg 2002;31:309-17. https://doi.org/10.1054/ijom.2002.0263
  6. Birn H. Etiology and pathogenesis of fibrinolytic alveolitis (“dry socket”). Int J Oral Surg 1973;2:211-63. https://doi.org/10.1016/S0300-9785(73)80045-6
  7. Tarakji B, Saleh LA, Umair A, Azzeghaiby SN, Hanouneh S. Systemic review of dry socket: aetiology, treatment, and prevention. J Clin Diagn Res 2015;9:ZE10-3.
  8. Fernandes GJ, Hatton MN. Prevention of alveolar osteitis. A case report and review of literature. N Y State Dent J 2016;82:21-5.
  9. Kolokythas A, Olech E, Miloro M. Alveolar osteitis: a comprehensive review of concepts and controversies. Int J Dent 2010;2010:249073.
  10. Fridrich KL, Olson RA. Alveolar osteitis following surgical removal of mandibular third molars. Anesth Prog 1990;37:32-41.
  11. Wates E, Ria B. The prevention and management of dry socket: do antibiotics have a role to play? Prim Dent J 2015;4:42-3. https://doi.org/10.1308/205016815815944696
  12. Hedstrom L, Sjogren P. Effect estimates and methodological quality of randomized controlled trials about prevention of alveolar osteitis following tooth extraction: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:8-15. https://doi.org/10.1016/j.tripleo.2006.01.007
  13. Nitzan DW. On the genesis of "dry socket". J Oral Maxillofac Surg 1983;41:706-10. https://doi.org/10.1016/0278-2391(83)90185-4
  14. Xu JL, Sun L, Liu C, Sun ZH, Min X, Xia R. Effect of oral contraceptive use on the incidence of dry socket in females following impacted mandibular third molar extraction: a meta-analysis. Int J Oral Maxillofac Surg 2015;44:1160-5. https://doi.org/10.1016/j.ijom.2015.05.017
  15. Jesudasan JS, Wahab PU, Sekhar MR. Effectiveness of 0.2% chlorhexidine gel and a eugenol-based paste on postoperative alveolar osteitis in patients having third molars extracted: a randomised controlled clinical trial. Br J Oral Maxillofac Surg 2015;53:826-30. https://doi.org/10.1016/j.bjoms.2015.06.022
  16. Khiyavi RK, Barghi VG, Yazdani J, Ghavimi MA, Khiyavi SG, Ebrahimi H. Effect of Biotene mouth wash on prevention of alveolar osteitis after extraction of permanent mandibular first molar teeth. Elixir Hum Physiol 2012;47:8672-4.
  17. Ross R, Glomset J, Kariya B, Harker L. A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sci U S A 1974;71:1207-10. https://doi.org/10.1073/pnas.71.4.1207
  18. Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, Dohan SL, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:299-303. https://doi.org/10.1016/j.tripleo.2005.07.012
  19. Haraji A, Lassemi E, Motamedi MH, Alavi M, Adibnejad S. Effect of plasma rich in growth factors on alveolar osteitis. Natl J Maxillofac Surg 2012;3:38-41. https://doi.org/10.4103/0975-5950.102150
  20. Pal US, Singh BP, Verma V. Comparative evaluation of zinc oxide eugenol versus gelatin sponge soaked in plasma rich in growth factor in the treatment of dry socket: an initial study. Contemp Clin Dent 2013;4:37-41. https://doi.org/10.4103/0976-237X.111592
  21. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e37-44. https://doi.org/10.1016/j.tripleo.2005.07.008
  22. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e45-50. https://doi.org/10.1016/j.tripleo.2005.07.009
  23. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e51-5. https://doi.org/10.1016/j.tripleo.2005.07.010
  24. Eshghpour M, Rezaei NM, Nejat A. Effect of menstrual cycle on frequency of alveolar osteitis in women undergoing surgical removal of mandibular third molar: a single-blind randomized clinical trial. J Oral Maxillofac Surg 2013;71:1484-9. https://doi.org/10.1016/j.joms.2013.05.004
  25. Ogundipe OK, Ugboko VI, Owotade FJ. Can autologous plateletrich plasma gel enhance healing after surgical extraction of mandibular third molars? J Oral Maxillofac Surg 2011;69:2305-10. https://doi.org/10.1016/j.joms.2011.02.014

피인용 문헌

  1. The impact of platelet-rich fibrin (PRF) on olfactory function and pain after septoplasty operations vol.277, pp.4, 2019, https://doi.org/10.1007/s00405-020-05839-6