Journal of the Korean Burn Society (대한화상학회지)

Korean Burn Society (대한화상학회)
권호 표지

Feasibility of Cultured Allogenic Keratinocyte Treatment for Third Degree Burns

3도 화상에 대한 동종 상피세포 치료제의 효과 보고

  • Choi, Jangyoun (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Cho, Jin Tae (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Choi, Jong Yun (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Seo, Bommie Florence (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jung, Sung-No (Department of Plastic and Reconstructive Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea)
  • 최장연 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 조진태 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 최종윤 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 서보미 (가톨릭대학교 의과대학 의정부성모병원 성형외과) ;
  • 정성노 (가톨릭대학교 의과대학 의정부성모병원 성형외과)
  • Received : 2019.10.17
  • Accepted : 2019.11.15
  • Published : 2019.12.31

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Abstract

Allogenic keratinocyte application is widely used for treatment of second degree burns. However, there is no significant body of report on application of allogenic keratinocyte to third degree burns. A geriatric patient visited our burn center showing second to third-degree burn on dorsum of her left hand. Considering the surface area and wound depth, surgery was indicated but her medical condition and age made the surgery high risk for a long operation. Therefore, chemical escharolysis, serial bedside debridement, and cultured allogenic keratinocyte (Kaloderm®, Tegoscience, Seoul, Korea) application was done. The wound was completely epithelialized after four rounds of Kaloderm® application. For third-degree burns where definitive surgical reconstruction is precluded due to medical comorbidity of the patient, we investigated the possibility of allogenic keratinocyte treatment which may allow to avoid high-risk anesthesia and surgery.

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