DOI QR코드

DOI QR Code

Metabolic Engineering for Improved Fermentation of L-Arabinose

  • Ye, Suji (School of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Jeong-won (School of Food Science and Biotechnology, Kyungpook National University) ;
  • Kim, Soo Rin (School of Food Science and Biotechnology, Kyungpook National University)
  • 투고 : 2018.12.10
  • 심사 : 2019.01.29
  • 발행 : 2019.03.28

초록

L-Arabinose, a five carbon sugar, has not been considered as an important bioresource because most studies have focused on D-xylose, another type of five-carbon sugar that is prevalent as a monomeric structure of hemicellulose. In fact, L-arabinose is also an important monomer of hemicellulose, but its content is much more significant in pectin (3-22%, g/g pectin), which is considered an alternative biomass due to its low lignin content and mass production as juice-processing waste. This review presents native and engineered microorganisms that can ferment L-arabinose. Saccharomyces cerevisiae is highlighted as the most preferred engineering host for expressing a heterologous arabinose pathway for producing ethanol. Because metabolic engineering efforts have been limited so far, with this review as momentum, more attention to research is needed on the fermentation of L-arabinose as well as the utilization of pectin-rich biomass.

키워드

참고문헌

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