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Treatment of Melting Ulcer in a Foal

망아지에서 발생한 녹는궤양(Melting Ulcer)의 치료

  • Bae, Yeong-rim (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Lee, Eun-bee (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Song, Mingeun (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Lee, Joo-myoung (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Kang, Tae-Young (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Seo, Jong-pil (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 배영림 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 이은비 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 송민근 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 이주명 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 강태영 (제주대학교 수의과대학 및 수의과학연구소) ;
  • 서종필 (제주대학교 수의과대학 및 수의과학연구소)
  • Received : 2018.07.06
  • Accepted : 2018.07.30
  • Published : 2019.02.28

Abstract

A 6-month-old male thoroughbred foal with melting ulcer after left eye trauma was referred to Equine Hospital of Jeju National University. The left eye did not respond to the menace reflex test. Bacteria were not observed on corneal smear and culture test, and fluorescein staining revealed corneal injury. Subpalpebral Lavage (SPL) catheter was installed through the upper left eyelid. And the antibiotics, mydriatic and antifungal agents were administered using SPL. In addition, temporary tarsorrhaphy was performed and a hard cup hood was applied. After 2 weeks, the temporary tarsorrhaphy was removed and severe corneal neovascularization was found. On the 39th day of treatment, the left eye was responding to the menace reflex test and granular tissue formation was confirmed in the ulcer area. During the 2 months follow-up, we found that the granulation tissues decreased significantly. This case report describes a successful recovery of severe melting ulcers in a foal by intensive treatment.

Keywords

References

  1. Brooks DE, Matthews AG. Equine ophthalmology. In: Gelatt KN (ed). Veterinary Ophthalmology, 4th edn. Ames: Wiley Blackwell. 2007: 1165-1274.
  2. Brooks DE. Ophthalmology for the Equine Practitioner, 2nd edn. Jackson: Teton NewMedia, 2008.
  3. Cameron JD. Chapter 8: Corneal reaction to injury. In: Krachmer JH, Mannis MJ, Holland EJ (eds). Cornea: Fundamentals of Cornea and External Disease Vol 1. St Louis: Mosby. 1997: 163-182.
  4. Clode AB. Diseases and surgery of the cornea. In: Gilger BC (ed). Equine Ophthalmology, 2nd edn. Maryland Heights: Elsevier Saunders. 2011: 181-266.
  5. Clode AB. Diseases of the cornea. In: Gilger BC (ed). Equine Ophthalmology, 3rd edn. Ames, Iowa : John Wiley & Sons Inc. 2017: 252-368.
  6. Grahn BH, Peiffer RL Jr. Veterinary ophthalmology pathology. In: Gelatt KN, Gilger BC, Kern TJ (eds). Veterinary Ophthalmology, 5th ed. Ames: Wiley Blackwell. 2013: 435-523.
  7. Hollingsworth SR. Diseases of the uvea. In: Gilger BC (ed). Equine Ophthalmology, 2nd edn. Maryland Heights: Elsevier Saunders. 2011: 267-281.
  8. Kleinfeld J, Ellis PP. Inhibition of microorganisms by topical anesthetics, Appl Microbiol 1967; 15: 1296-1298. https://doi.org/10.1128/AEM.15.6.1296-1298.1967
  9. Mark P. Nasisse, Susan Nelms. Equine Ulcerative Keratitis. In: Veterinary Clinics of North America: Equine Practice, Vol 8. St. Louis: Elsevier. 1992: 537-555.
  10. Massa KL, Murphy CJ, Hartmann FA, Miller PE, Korsower CS, Young KM. Usefulness of aerobic microbial cultures and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis in animals. J Am Vet Med Assoc 1999; 215: 1671-1674.
  11. McLaughlin SA, Brightman AH, Helper LC, Manning JP, Tomes JE. Pathogenic bacteria and fungi associated with extraocular disease in the horse. J Am Vet Med Assoc 1983; 182: 241-242.
  12. Moore CP, Fales WH, Whittington P, Bauer L. Bacterial and fungal isolates from equidae with ulcerative keratitis. J Am Vet Med Assoc 1983; 182: 600-603.
  13. Strubbe DT, Brooks DE, Schultz GS, Willis-Goulet H, Gelatt KN, Andrew SE, Kallberg ME, MacKay EO, Collante WR. Evaluation of tear film proteinases in horses with ulcerative keratitis. Vet Ophthalmol 2000; 3: 111-120. https://doi.org/10.1046/j.1463-5224.2000.00093.x
  14. Traver DS, Riviere JE, Coppoc GL, Hinsman EJ, Carlton WW. Species Dependent Gentamicine Pharmacokinetics and Nephrotoxicity in the Young Horse. Toxicological Sciences 1983; 3: 448-457. https://doi.org/10.1093/toxsci/3.5.448
  15. Whitley RE. Neonatal equine ophthalmology. In: Koterba AM, Drummond WH, Kosche PC (eds). Equine Clinical Neonatology. Philadelphia: Lea & Febiger. 1990: 531-557.