Journal of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회지)

Korean Society of Radiopharmaceuticals and Molecular Probes (대한방사성의약품학회)
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Preliminary studies for production of 61Cu using natural nickel target with RFT-30 cyclotron

  • Lee, Jun Young (Department of Radiation Research, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Hur, Min Goo (Department of Radiation Research, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Yang, Seung Dae (Department of Radiation Research, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Park, Jeong Hoon (Department of Radiation Research, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
  • Received : 2019.12.16
  • Accepted : 2019.12.28
  • Published : 2019.12.30
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Abstract

61Cu is a promising PET radiometal having favorable nuclear decay characteristics with appropriate half-life of 3.3 h. Owing its promising capabilities in radiopharmaceutical chemistry and its chemical similarities with its isotopes 64Cu and 67Cu, in this work we have tried to optimize the production and separation conditions of 61Cu. 61Cu was produced via (p, x) reaction with natural nickel which was electroplated on the high purity silver coated copper backing target holder. The optimization of target electrodeposition, beam energy and current modulation, target dissolution and separation were optimized in this study. Preliminary studies show that 61Cu was successfully produced and separated which can be further extended for the production of 64Cu and 67Cu.

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References

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