DOI QR코드

DOI QR Code

일시적 혈압상승에 대한 황련해독탕 과립제의 효과 : 증례 보고

Effects of Huanglianjiedu-tang Granules for Transient Elevated Blood Pressure: A Case Series

  • 투고 : 2019.11.25
  • 심사 : 2020.01.02
  • 발행 : 2019.12.30

초록

Objective: This study reports the effects of Huanglianjiedu-tang (黃連解毒湯) granules as a treatment for transient hypertension. Methods: Four patients experienced sudden blood pressure elevation without a history of hypertension treatment. There was no specific history of disease, as confirmed by laboratory examination and image diagnosis. The patients were treated with Huanglianjiedu-tang (黃連解毒湯) granules and their blood pressure analyzed over time. Results: After treatment with Huanglianjiedu-tang granules, the mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) of all patients decreased significantly. Conclusions: The study suggests that Huanglianjiedu-tang (黃連解毒湯) granules could be a primary treatment for hypertension. A well-designed study should be conducted for further evaluation of the effectiveness of the treatment.

키워드

참고문헌

  1. Kim HC, Cho MC. Korea hypertension fact sheet 2018. Clinical hypertension 2018;24(1):13. https://doi.org/10.1186/s40885-018-0098-0
  2. Thomopoulos C, Parati G, Zanchetti A. Effects of blood-pressure-lowering treatment on outcome incidence. 12. Effects in individuals with highnormal and normal blood pressure: overview and meta-analyses of randomized trials. Journal of hypertension 2017;35(11):2150-60. https://doi.org/10.1097/HJH.0000000000001547
  3. Collaboration PS. Age-specific relevance of usual blood pressure to vascular mortality: a metaanalysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360(9349):1903-13. https://doi.org/10.1016/S0140-6736(02)11911-8
  4. Chen H, Shen FE, Tan XD, Jiang WB, Gu YH. Efficacy and safety of acupuncture for essential hypertension: a meta-analysis. Medical science monitor: international medical journal of experimental and clinical research 2018;24:2946-69. https://doi.org/10.12659/MSM.909995
  5. Liao HH, Yeh CC, Lin CC, Chen BC, Yeh MH, Chang KM, et al. Prescription patterns of Chinese herbal products for patients with fractures in Taiwan: a nationwide population-based study. Journal of ethnopharmacology 2015;173:11-9. https://doi.org/10.1016/j.jep.2015.07.014
  6. Xiong X, Wang P, Zhang Y, Li X Effects of traditional Chinese patent medicine on essential hypertension: a systematic review. Medicine 2015;94(5):e442. https://doi.org/10.1097/MD.0000000000000442
  7. Li CB, Li XX, Chen YG, Gao HQ, Bu PL, Zhang Y, et al. Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance. PloS one 2013;8(6):e67530. https://doi.org/10.1371/journal.pone.0067530
  8. Arakawa K, Saruta T, Abe K, Iimura O, Ishii M, Ogihara T, et al. Improvement of accessory symptoms of hypertension by TSUMURA Orengedokuto Extract, a four herbal drugs containing Kampo-Medicine Granules for ethical use: a double-blind, placebo-controlled study. Phytomedicine 2006;13(1-2):1-10. https://doi.org/10.1016/j.phymed.2004.02.012
  9. American College of Cardiology. Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. J Am Coll Cardiol 2017;4-28.
  10. Qaseem A, Wilt TJ, Rich R, Humphrey LL, Frost J, Forciea MA. Pharmacologic treatment of hypertension in adults aged 60 years or older to higher versus lower blood pressure targets: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Annals of internal medicine 2017;166(6):430-7. https://doi.org/10.7326/m16-1785
  11. Tong XL, Lian FM, Zhou Q, Xu LP, Ji HY, Xu GC, et al. A prospective multicenter clinical trial of Chinese herbal formula JZQG (Jiangzhuoqinggan) for hypertension. The American journal of Chinese medicine 2013;41(1):33-42. https://doi.org/10.1142/S0192415X13500031
  12. Peng W, Lauche R, Ferguson C, Frawley J, Adams J, Sibbritt D. Efficacy of Chinese herbal medicine for stroke modifiable risk factors: a systematic review. Chinese medicine 2017;12(1):25. https://doi.org/10.1186/s13020-017-0146-9
  13. Zhang C, Zhao R, Yan W, Wang H, Jia M, Zhu N. Compositions, formation mechanism, and neuroprotective effect of compound precipitation from the traditional chinese prescription huang-lian-jie-du-tang. Molecules 2016;21(8):1094. https://doi.org/10.3390/molecules21081094
  14. Li GZ, He Z, Shao FF, Ou AH, Lin XZ. Patient classification of hypertension in Traditional Chinese Medicine using multi-label learning techniques. BMC medical genomics 2015;8(3):S4.