The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
권호 표지
DOI QR코드

DOI QR Code

Difference in Injury of the Corticospinal Tract and Spinothalamic Tract in Patients with Putaminal Hemorrhage

  • Jang, Sung Ho (Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University) ;
  • Seo, Jeong Pyo (Department of Physical Therapy, College of Health Sciences, Dankook University)
  • Received : 2019.11.04
  • Accepted : 2019.12.27
  • Published : 2019.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: We investigated the difference in injury of the corticospinal tract (CST) and the spinothalamic tract (STT) in patients with putaminal hemorrhage, using diffusion tensor tractography (DTT). Methods: Thirty one consecutive patients with PH and 34 control subjects were recruited for this study. DTT scanning was performed at early stage of PH (7-63 days), and the CST and STT were reconstructed using the Functional Magnetic Resonance Imaging of Brain (FMRIB) Software Library program. Injury of the CST and STT was defined in terms of the configuration or abnormal DTT parameters was more than 2 standard deviations lower than that of normal control subjects. Results: Among 31 patients, all 31 patients (100%) had injury of the CTS, whereas 25 patients (80.6%) had injury of the STT: the incidence of CST injury was significantly higher than that of STT (p<0.05). In detail, 20 (64.5%) of 31 patients showed a discontinuation of the CST in the affected hemisphere; in contrast, 14 patients (45.2%) of 31 patients showed a discontinuation of the STT in the affected hemisphere. Regarding the FA value, 6 (19.4%) of 31 patients and 2 (6.4%) of 31 patients were found to have injury in the CST and STT, respectively. In terms of the fiber number, the same injury incidence was observed in 11 patients (35.5%) in both the CST and STT. Conclusion: The greater vulnerability of the CST appears to be ascribed to the anatomical characteristics; the CST is located anteriorly to the center of the putamen compared with the STT.

Keywords

References

  1. Inagawa T, Ohbayashi N, Takechi A et al. Primary intracerebral hemorrhage in izumo city, japan: Incidence rates and outcome in relation to the site of hemorrhage. Neurosurgery. 2003;53(6):1283-97. https://doi.org/10.1227/01.neu.0000093825.04365.f3
  2. Bogousslavsky J, Caplan LR. Stroke syndromes. 2nd. Cambridge, New York, Cambridge University Press, 2001.
  3. Jang SH. A review of corticospinal tract location at corona radiata and posterior limb of the internal capsule in human brain. NeuroRehabilitation. 2009;24(3):279-83. https://doi.org/10.3233/nre-2009-0479
  4. Jang SH. The corticospinal tract from the viewpoint of brain rehabilitation. J Rehabil Med. 2014;46(3):193-9. https://doi.org/10.2340/16501977-1782
  5. Afifi AK, Bergman RA. Functional neuroanatomy: Text and atlas. 2nd. New York, Lange Medical Books/McGraw-Hill, 2005.
  6. Mendoza JE, Foundas AL. Clinical neuroanatomy: A neurobehavioral approach. New York, Springer, 2007.
  7. Kim JH, Ahn SH, Cho YW et al. The relation between injury of the spinothalamocortical tract and central pain in chronic patients with mild traumatic brain injury. J Head Trauma Rehabil. 2015;31(6):E40-6.
  8. Smith SM, Jenkinson M, Woolrich MW et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage. 2004;23 Suppl 1:S208-19. https://doi.org/10.1016/j.neuroimage.2004.07.051
  9. Jiang H, van Zijl PC, Kim J et al. Dtistudio: Resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed. 2006;81(2):106-16. https://doi.org/10.1016/j.cmpb.2005.08.004
  10. Jang SH. Somatotopic arrangement and location of the corticospinal tract in the brainstem of the human brain. Yonsei Med J. 2011;52(4):553-7. https://doi.org/10.3349/ymj.2011.52.4.553
  11. Hong JH, Son SM, Jang SH. Identification of spinothalamic tract and its related thalamocortical fibers in human brain. Neurosci Lett. 2010; 468(2):102-5. https://doi.org/10.1016/j.neulet.2009.10.075
  12. Kwak R, Kadoya S, Suzuki T. Factors affecting the prognosis in thalamic hemorrhage. Stroke. 1983;14(4):493-500. https://doi.org/10.1161/01.str.14.4.493
  13. Mori S, Crain BJ, Chacko VP et al. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol. 1999;45(2):265-9. https://doi.org/10.1002/1531-8249(199902)45:2<265::AID-ANA21>3.0.CO;2-3
  14. Assaf Y, Pasternak O. Diffusion tensor imaging (DTI)-based white matter mapping in brain research: A review. J Mol Neurosci. 2008;34(1):51-61. https://doi.org/10.1007/s12031-007-0029-0
  15. Jang SH, Jang WH. Change of the corticospinal tract in the unaffected hemisphere by change of the dominant hand following stroke: A cohort study. Medicine (Baltimore). 2016;95(6):e2620. https://doi.org/10.1097/md.0000000000002620
  16. Parker GJ, Alexander DC. Probabilistic anatomical connectivity derived from the microscopic persistent angular structure of cerebral tissue. Philos Trans R Soc Lond B Biol Sci. 2005;360(1457):893-902. https://doi.org/10.1098/rstb.2005.1639
  17. Yamada K, Sakai K, Akazawa K et al. Mr tractography: A review of its clinical applications. Magn Reson Med Sci. 2009;8(4):165-74. https://doi.org/10.2463/mrms.8.165