Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
권호 표지
DOI QR코드

DOI QR Code

A Case of Acute Supraglottitis Following Anti-Thyroid Drug-Induced Agranulocytosis

항갑상선제 부작용으로 인한 무과립구증에 속발한 급성 성문상부염 1예

  • Lee, Jung Jun (Department of Otolaryngology, Ajou University School of Medicine) ;
  • Kim, Dong Young (Department of Otolaryngology, Ajou University School of Medicine) ;
  • Jang, Jeon Yeob (Department of Otolaryngology, Ajou University School of Medicine)
  • 이정준 (아주대학교 의과대학 이비인후과학교실) ;
  • 김동영 (아주대학교 의과대학 이비인후과학교실) ;
  • 장전엽 (아주대학교 의과대학 이비인후과학교실)
  • Received : 2019.07.02
  • Accepted : 2019.08.06
  • Published : 2019.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

Acute supraglottitis is characterized by an inflammation and edema of the supraglottic region and a potential life-threatening condition because of its risk for sudden upper airway compromise. Prompt diagnosis, administration of broad spectrum antibiotics, and airway management is pivotal for reducing serious complications. In the immunocompromised host, microorganisms are more likely to elicit mucosal inflammations, thus clinicians should pay attention to those patients for prompt removal of the causes of immune disruption. Here we report a case of acute adult supraglottitis with neutropenia caused by anti-thyroid drug with a review of the related literatures.

Keywords

References

  1. Byun JY, Lee BH, Hwang JH, Jin DS, Chai YH, Lee KO. Acute supraglottitis in adults. Korean J Otorhinolaryngol-Head Neck Surg 1995;38(8):1251-6.
  2. Navaratnam AV, Smith ME, Majeed A, McFerran DJ. Adult supraglottitis: a potential airway emergency that can present in primary care. Br J Gen Pract 2015;65(631):99-100. https://doi.org/10.3399/bjgp15X683653
  3. Kim BJ, Choi BG, Choi HG, Lee JY, Park BJ. A clinical study of acute epiglottitis: retrospective review of 315 patients in Korea. Korean J Otorhinolaryngol-Head Neck Surg 2019;62(4):233-7. https://doi.org/10.3342/kjorl-hns.2018.00430
  4. Guldfred LA, Lyhne D, Becker BC. Acute epiglottitis: epidemiology, clinical presentation, management and outcome. J Laryngol Otol 2008;122(8):818-23. https://doi.org/10.1017/S0022215107000473
  5. Al-Qudah M, Shetty S, Alomari M, Alqdah M. Acute adult supraglottitis: current management and treatment. South Med J 2010;103(8):800-4. https://doi.org/10.1097/SMJ.0b013e3181e538d8
  6. Shah RK, Stocks C. Epiglottitis in the United States: national trends, variances, prognosis, and management. Laryngoscope 2010;120(6):1256-62. https://doi.org/10.1002/lary.20921
  7. Lee ACW, Lam SY. Life threatening acute epiglottitis in acute leukemia. Leuk Lymphoma 2002;43(3):665-7. https://doi.org/10.1080/10428190290012254
  8. Chen C, Natarajan M, Bianchi D, Aue G, Powers JH. Acute epiglottitis in the immunocompromised host: case report and review of the literature. Open Forum Infect Dis 2018;5(3):ofy038. https://doi.org/10.1093/ofid/ofy038
  9. Nagaraja V, Stewart TE, Mackay SG, Glenn DW, Wakefield D, Boutlis CS. Supraglottitis due to group B streptococcus in an adult with IgG4 and C2 deficiency: a case report and review of the literature. Laryngoscope 2015;125(4):852-5. https://doi.org/10.1002/lary.24874
  10. Vicente N, Cardoso L, Barros L, Carrilho F. Antithyroid drug-induced agranulocytosis: state of the art on diagnosis and management. Drugs R D 2017;17(1):91-6. https://doi.org/10.1007/s40268-017-0172-1
  11. Guardiani E, Bliss M, Harley E. Supraglottitis in the era following widespread immunization against Haemophilus influenzae type B: evolving principles in diagnosis and management. Laryngoscope 2010;120(11):2183-8. https://doi.org/10.1002/lary.21083
  12. Bizaki AJ, Numminen J, Vasama JP, Laranne J, Rautiainen M. Acute supraglottitis in adults in Finland: review and analysis of 308 cases. Laryngoscope 2011;121(10):2107-13. https://doi.org/10.1002/lary.22147
  13. Kim HK, Yoon JH, Jeon MJ, Kim TY, Shong YK, Lee MJ, et al. Characteristics of Korean patients with antithyroid drug-induced agranulocytosis: a multicenter study in Korea. Endocrinol Metab (Seoul) 2015;30(4):475-80. https://doi.org/10.3803/EnM.2015.30.4.475
  14. Cooper DS. Antithyroid drugs. N Engl J Med 2005;352(9):905-17. https://doi.org/10.1056/NEJMra042972
  15. Fukata S, Kuma K, Sugawara M. Granulocyte colony-stimulating factor (G-CSF) does not improve recovery from antithyroid drug-induced agranulocytosis: a prospective study. Thyroid 1999;9(1):29-31. https://doi.org/10.1089/thy.1999.9.29